ReviewAmerican journal of human genetics2011
Insights into the pathogenesis and treatment of cancer from inborn errors of metabolism.
Review in American journal of human genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 66 citations in OpenAlex.
- Advancing cancer therapy: Nanomaterial-based encapsulation strategies for enhanced delivery and efficacy of curcumin.Materials today. Bio · 2025Review
- Combining Metabolomics and Machine Learning to Identify Diagnostic and Prognostic Biomarkers in Patients with Non-Small Cell Lung Cancer Pre- and Post-Radiation Therapy.Biomolecules · 2024Article
- Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable Isotopes.Metabolites · 2024Article
- Report of an Iranian child with chronic abdominal pain and constipation diagnosed as glycogen storage disease type IX: a case report.Journal of medical case reports · 2024Article
- The Complexities of Diagnosis with Co-Existing Gaucher Disease and Hemato-Oncology-A Case Report and Review of the Literature.Journal of clinical medicine · 2023Review
- Cancer risk and gammopathies in 2123 adults with Gaucher disease type 1 in the International Gaucher Group Gaucher Registry.American journal of hematology · 2022Observational
- Genetic impairment of succinate metabolism disrupts bioenergetic sensing in adrenal neuroendocrine cancer.Cell reports · 2022Article
- Clinical and biochemical footprints of inherited metabolic diseases. VIII. Neoplasias.Molecular genetics and metabolism · 2022Review
- Targeting Metabolic Plasticity and Flexibility Dynamics for Cancer Therapy.Cancer discovery · 2020Review
- Update on Alpha-1 Antitrypsin Deficiency in Liver Disease.Clinical liver disease · 2020Review
- Hepatocellular Adenoma in a Patient with Ornithine Transcarbamylase Deficiency.Case reports in hepatology · 2019Article
- Molecular and clinical characterization of citrin deficiency in a cohort of Chinese patients in Hong Kong.Molecular genetics and metabolism reports · 2018Article
- Renal cell carcinoma harboring somatic TSC2 mutations in a child with methylmalonic acidemia.Pediatric blood & cancer · 2017Article
- Involvement of Ornithine Carbamoyltransferase in the Progression of Chronic Hepatitis C and Liver Cirrhosis.International journal of medical sciences · 2017Article
- Liposomal curcumin and its application in cancer.International journal of nanomedicine · 2017Review
- Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.Journal of the American Chemical Society · 2016Article
- Pharmacokinetics and biodistribution of recently-developed siRNA nanomedicines.Advanced drug delivery reviews · 2016Review
- Demographic and Clinical Findings in Pediatric Patients Affected by Organic Acidemia.Iranian journal of child neurology · 2016Article
- Metabolic dysregulation in monogenic disorders and cancer - finding method in madness.Nature reviews. Cancer · 2015Review
- Mitochondrial ferritin, a new target for inhibiting neuronal tumor cell proliferation.Cellular and molecular life sciences : CMLS · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Mutations in genes that play fundamental roles in metabolic pathways have been found to also play a role in tumor development and susceptibility to cancer. At the same time, significant progress has been made in the treatment of patients with inborn errors of metabolism (IEM),(1) resulting in increased longevity and the unmasking of cancer predisposition, frequently hepatocellular carcinoma, in these conditions. These patients offer a potential opportunity to deepen our understanding of how intermediary metabolism impacts tumorigenesis. We provide an overview from the perspective of cancers in patients affected with IEM and discuss how dysregulation of these specific metabolic pathways might contribute to the mechanisms of cancer development and treatment.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.