Evidence map›Paper›PMID 21473914›Full record

ReviewPharmacological research2011

Green tea and bone health: Evidence from laboratory studies.

Chwan-Li Shen, James K Yeh, Jay J Cao, Ming-Chien Chyu, Jia-Sheng Wang

Registry-linked trialAbstract readReview
In one paragraph

Review in Pharmacological research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00625391 (GTP and Tai Chi for Bone Health), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00625391 phase1 / phase2completednot on this map

GTP and Tai Chi for Bone Health: a Pilot Study

TypeinterventionalSponsorTexas Tech University Health Sciences CenterRan2008 to 2009Enrolled171ConditionsOsteoporosisArmsPlacebo, Green Tea Polyphenols (GTP), Placebo+Tai Chi (TC), GTP+TC
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Green tea (Food & nutrition research · 2018
    Article
  11. Article
  12. Article
  13. Molecular signaling mechanisms behind polyphenol-induced bone anabolism.Phytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2017
    Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Does tea consumption correlate to risk of fracture? A meta-analysis.International journal of clinical and experimental medicine · 2015
    Review
  20. The effects of flavonoids on bone.Current osteoporosis reports · 2014
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Chwan-Li ShenDepartment of Pathology, Texas Tech University Health Sciences Center, Lubbock, TX 79430-9097, USA. leslie.shen@ttuhsc.edu
James K Yeh
Jay J Cao
Ming-Chien Chyu
Jia-Sheng Wang
Texas Tech University · USGrand Forks Human Nutrition Research Center · USUniversity of Georgia · USWinthrop-University Hospital · US

Funding

GTP and Tai Chi for Bone Health: a Pilot StudyR21AT003735 · NCCIH · TEXAS TECH UNIVERSITY HEALTH SCIS CENTER · PI SHEN, CHWAN-LI L · 2007 to 2008
$568k
NCCIH NIH HHS R21 AT003735NCCIH NIH HHS R21AT003735
6 · The paper itself

Abstract

Osteoporosis is a major health problem in the elderly. Epidemiological evidence has shown an association between tea consumption and the prevention of bone loss in the elderly population. Ingestion of green tea and green tea bioactive compounds may be beneficial in mitigating bone loss of this population and decreasing their risk of osteoporotic fractures. This review describes the effect of green tea with its bioactive components on bone health with an emphasis on the following: (i) the etiology of osteoporosis, (ii) evidence of osteo-protective impacts of green tea on bone mass and microarchitecture in various bone loss models in which induced by aging, sex hormone deficiency, and chronic inflammation, (iii) discussion of impacts of green tea on bone mass in two obesity models, (iv) observation of short-term green tea supplementation given to postmenopausal women with low bone mass, (v) possible mechanisms for the osteo-protective effects of green tea bioactive compounds, and (vi) a summary and future research direction of green tea and bone health.

Indexed as

TeaAnimalsBone and BonesBone DensityHumansOsteoporosis, PostmenopausalOsteoporotic FracturesTea

Identifiers

PMID21473914
PMCPMC3123403
OpenAlexW2078714098

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.