ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2011
Determination of genetic structure of germplasm collections: are traditional hierarchical clustering methods appropriate for molecular marker data?
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- Nuclear DNA Amount in a Diverse Collection ofInternational journal of molecular sciences · 2026Article
- Genetic Diversity and Population Structure of 72 Turkish Ficus carica (L.) Genotypes Assessed Using SCoT Markers.Biochemical genetics · 2026Article
- Nuclear DNA Content Analyses by Flow Cytometry of Saffron (Current issues in molecular biology · 2026Article
- Evidence of early genomic selection in Holstein Friesian across African and European ecosystems.BMC genomics · 2025Article
- Article
- Whole-genome sequencing reveals genetic diversity, population structure, and core collection construction in Korean peach (Frontiers in plant science · 2025Article
- Article
- Exploring the secrets of super-aging: a UK Biobank study on brain health and cognitive function.GeroScience · 2023Article
- Genome-Wide Association Study for Agro-Morphological Traits in Eggplant Core Collection.Plants (Basel, Switzerland) · 2022Article
- Recent advancement in OMICS approaches to enhance abiotic stress tolerance in legumes.Frontiers in plant science · 2022Review
- Population Structure and Relatedness for Genome-Wide Association Studies.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Construction of a core collection of native Perilla germplasm collected from South Korea based on SSR markers and morphological characteristics.Scientific reports · 2021Article
- Population structure and genetic diversity of the Pee Dee cotton breeding program.G3 (Bethesda, Md.) · 2021Article
- Influence of Environmental Factors on the Genetic and Chemical Diversity ofPlants (Basel, Switzerland) · 2021Article
- Deciphering genetic diversity analysis of saffron (Saudi journal of biological sciences · 2021Article
- Assessment of genetic diversity and population structure among a collection of Korean Perilla germplasms based on SSR markers.Genes & genomics · 2020Article
- Assessing countries' performances against COVID-19 via WSIDEA and machine learning algorithms.Applied soft computing · 2020Article
- Molecular and phenotypic diversity of groundnut (Physiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Article
- StructuRly: A novel shiny app to produce comprehensive, detailed and interactive plots for population genetic analysis.PloS one · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the availability of newer approaches, traditional hierarchical clustering remains very popular in genetic diversity studies in plants. However, little is known about its suitability for molecular marker data. We studied the performance of traditional hierarchical clustering techniques using real and simulated molecular marker data. Our study also compared the performance of traditional hierarchical clustering with model-based clustering (STRUCTURE). We showed that the cophenetic correlation coefficient is directly related to subgroup differentiation and can thus be used as an indicator of the presence of genetically distinct subgroups in germplasm collections. Whereas UPGMA performed well in preserving distances between accessions, Ward excelled in recovering groups. Our results also showed a close similarity between clusters obtained by Ward and by STRUCTURE. Traditional cluster analysis can provide an easy and effective way of determining structure in germplasm collections using molecular marker data, and, the output can be used for sampling core collections or for association studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.