Evidence map›Paper›PMID 21470887›Full record

ReviewGrowth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society2011

Growth hormone and adipose tissue: beyond the adipocyte.

Darlene E Berryman, Edward O List, Lucila Sackmann-Sala, Ellen Lubbers, Rachel Munn, John J Kopchick

Abstract readReview
In one paragraph

Review in Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 82 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Growth hormone receptor gene disruption.Vitamins and hormones · 2023
    Article
  8. Growth Hormone, Not IGF-1 Is the Key Longevity Regulator in Mammals.The journals of gerontology. Series A, Biological sciences and medical sciences · 2022
    Article
  9. Article
  10. Review
  11. Tissue-specific disruption of the growth hormone receptor (GHR) in mice: An update.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2020
    Review
  12. Acromegaly is associated with high fibroblast growth factor-21 levels.Journal of endocrinological investigation · 2019
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Increased fibrosis: A novel means by which GH influences white adipose tissue function.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2018
    Article
  18. Growth Hormone's Effect on Adipose Tissue: Quality versus Quantity.International journal of molecular sciences · 2017
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Darlene E BerrymanSchool of Applied Health Sciences and Wellness College of Health Sciences and Human Performance, Ohio University, Athens, OH 45701, United States. berrymad@ohio.edu
Edward O List
Lucila Sackmann-Sala
Ellen Lubbers
Rachel Munn
John J Kopchick
Ohio University · USBiotechnology Institute · US

Funding

The Somatotropic Axis and Health Aging: A Search for MechanismsP01AG031736 · NIA · SOUTHERN ILLINOIS UNIVERSITY SCH OF MED · PI KIRKLAND, JAMES L. · 2009 to 2013
$8.4M
NIA NIH HHS AG031736NIA NIH HHS P01 AG031736
6 · The paper itself

Abstract

The last two decades have seen resurgence in research focused on adipose tissue. In part, the enhanced interest stems from an alarming increase in obesity rates worldwide. However, an understanding that this once simple tissue is significantly more intricate and interactive than previously realized has fostered additional attention. While few would argue that growth hormone (GH) radically alters fat mass, newer findings revealing the complexity of adipose tissue requires that GH's influence on this tissue be reexamined. Therefore, the objective of this review is to describe the more recent understanding of adipose tissue and to summarize our current knowledge of how GH may influence and contribute to these newer complexities of this tissue with special focus on the available data from mice with altered GH action.

Indexed as

AdipocytesAdipose TissueAnimalsBody CompositionExtracellular MatrixGrowth HormoneHumansMiceGrowth Hormone

Identifiers

PMID21470887
PMCPMC3112270
OpenAlexW2079607096

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.