Evidence map›Paper›PMID 21470604›Full record

ArticleGastrointestinal endoscopy2011

Carcinomatosis is not a contraindication to enteral stenting in selected patients with malignant gastric outlet obstruction.

Robin B Mendelsohn, Hans Gerdes, Arnold J Markowitz, Christopher J DiMaio, Mark A Schattner

Abstract read
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In one paragraph

Article in Gastrointestinal endoscopy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 74 citations in OpenAlex.

  1. Article
  2. Article
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  4. [Palliative endoscopy].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2022
    Article
  5. Review
  6. Review
  7. Endoscopic management of malignant gastric outlet obstruction.Journal of the Chinese Medical Association : JCMA · 2021
    Article
  8. Article
  9. Review
  10. Article
  11. The utility and efficacy of self-expandable metal stents for treating malignant gastric outlet obstructions in patients under best supportive care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  12. Article
  13. Endoscopic Palliation of Pancreatic Cancer.Current treatment options in gastroenterology · 2017
    Review
  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Robin B MendelsohnGastroenterology and Nutrition Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA. mendelsr@mskcc.org
Hans Gerdes
Arnold J Markowitz
Christopher J DiMaio
Mark A Schattner
Memorial Sloan Kettering Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopically inserted self-expandable metal stents (SEMSs) are used to palliate malignant gastric outlet obstruction (GOO). Peritoneal disease is considered a relative contraindication to SEMS placement given the risk of multifocal obstruction.

objectiveTo evaluate the success of SEMSs placed in patients with GOO with carcinomatosis.

designRetrospective review of patients who underwent SEMS placement for malignant GOO.

settingLarge, urban cancer center. PATIENTS: A total of 215 patients who were scheduled for SEMS placement for GOO.

interventionsSEMS placement. MAIN OUTCOME MEASUREMENTS: Technical success, clinical success, early and late SEMS failure, and complications.

resultsTechnical success was achieved in 192 of 201 patients (95.5%). Of the 9 patients who did not achieve technical success, 6 had carcinomatosis. Among the 116 patients (60%) with carcinomatosis, clinical success was achieved 94 of them (81%). Of these 94 patients, 17 (18%) required reinterventions: 4 for early SEMS failure and 13 for late SEMS failure. Among the 76 patients (40%) without carcinomatosis, clinical success was achieved in 64 of them (84%). Of these 64 patients, 17 (27%) required reinterventions: 4 for early SEMS failure and 13 for late SEMS failure. Complication rates were similar for both groups. LIMITATIONS: This was a retrospective review with experienced clinicians selecting patients whom they thought would benefit from SEMS placement.

conclusionsThis is the first study to evaluate the effect of carcinomatosis on the technical and clinical success of SEMSs in the palliation of malignant GOO. We found clinical outcomes comparable to those without peritoneal disease. Carcinomatosis should not be considered a contraindication to SEMS placement in selected patients with malignant GOO.

Indexed as

Palliative CareStentsAgedAscitesContraindicationsDigestive System NeoplasmsEndoscopy, GastrointestinalEquipment FailureFemaleGastric Outlet ObstructionHumansMaleMiddle AgedReoperationRetrospective StudiesTreatment Outcome

Identifiers

PMID21470604
OpenAlexW2071134908

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.