ArticleEmerging infectious diseases2011
Genome sequence of SG33 strain and recombination between wild-type and vaccine myxoma viruses.
Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 58 citations in OpenAlex.
- Molecular Mechanisms of Poxvirus Evolution.mBio · 2023Review
- Capripoxviruses, leporipoxviruses, and orthopoxviruses: Occurrences of recombination.Frontiers in microbiology · 2022Review
- ALG3 contributes to stemness and radioresistance through regulating glycosylation of TGF-β receptor II in breast cancer.Journal of experimental & clinical cancer research : CR · 2021Article
- Punctuated Evolution of Myxoma Virus: Rapid and Disjunct Evolution of a Recent Viral Lineage in Australia.Journal of virology · 2019Article
- Analysis and insights into recombination signals in lumpy skin disease virus recovered in the field.PloS one · 2018Article
- Genetic Variability of Myxoma Virus Genomes.Journal of virology · 2017Article
- Review
- Recombination of Globally Circulating Varicella-Zoster Virus.Journal of virology · 2015Article
- Review
- Diversity of avipoxviruses in captive-bred Houbara bustard.Veterinary research · 2014Article
- Article
- Genome scale evolution of myxoma virus reveals host-pathogen adaptation and rapid geographic spread.Journal of virology · 2013Article
- Comparative analysis of the complete genome sequence of the California MSW strain of myxoma virus reveals potential host adaptations.Journal of virology · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myxomatosis in Europe is the result of the release of a South America strain of myxoma virus in 1952. Several attenuated strains with origins in South America or California have since been used as vaccines in the rabbit industry. We sequenced the genome of the SG33 myxoma virus vaccine strain and compared it with those of other myxoma virus strains. We show that SG33 genome carries a large deletion in its right end. Furthermore, our data strongly suggest that the virus isolate from which SG33 is derived results from an in vivo recombination between a wild-type South America (Lausanne) strain and a California MSD-derived strain. These findings raise questions about the use of insufficiently attenuated virus in vaccination.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.