Evidence map›Paper›PMID 21470434›Full record

ArticleBMC gastroenterology2011

Pancreatic adenocarcinoma-associated polymyositis treated with corticosteroids along with cancer specific treatment: case report.

John Syrios, Georgios Kechagias, Ioannis D Xynos, Maria N Gamaletsou, Aristea Papageorgiou, George Agrogiannis, Nicolas Tsavaris

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC gastroenterology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Paraneoplastic myopathy in pancreatic cancer: a case report and literature review.Journal of community hospital internal medicine perspectives · 2021
    Article
  6. Review
  7. Review
  8. Evaluation and management of polymyositis.Indian journal of dermatology · 2012
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

John SyriosDepartment of Pathophysiology, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, Mikras Asias 75, 11527 Athens, Greece.
Georgios Kechagias
Ioannis D Xynos
Maria N Gamaletsou
Aristea Papageorgiou
George Agrogiannis
Nicolas Tsavaris
National and Kapodistrian University of Athens · GRLaiko General Hospital of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdenocarcinoma of the pancreas only rarely is associated with inflammatory myopathy. In this setting, polymyositis may be treated with glucocorticoids in combination with cancer specific treatment. CASE PRESENTATION: We present the case of a 52-year-old man with stage IIA pancreatic tail adenocarcinoma who underwent surgical treatment and six months into therapy with gemcitabine he developed symmetrical, painful, proximal muscle weakness with peripheral oedema. Re-evaluation with imaging modalities, muscle histology and biochemistry conferred the diagnosis of polymyositis associated with pancreatic cancer progression. The patient was treated with glucocorticoids along with gemcitabine and erlotinib which resulted in complete remission within six months. He remained in good health for a further six months on erlotinib maintenance therapy when a new computer tomography scan showed pancreatic cancer relapse and hence prompted 2nd line chemotherapy with gemcitabine.

conclusionsPolymyositis associated with pancreatic cancer may respond to glucocorticoids along with cancer specific treatment.

Indexed as

AdenocarcinomaAntimetabolites, AntineoplasticCD8-Positive T-LymphocytesDeoxycytidineErlotinib HydrochlorideGemcitabineGlucocorticoidsHumansMaleMiddle AgedPancreatic NeoplasmsPolymyositisQuinazolinesRadionuclide ImagingAntimetabolites, AntineoplasticDeoxycytidineErlotinib HydrochlorideGemcitabineGlucocorticoidsQuinazolines

Identifiers

PMID21470434
PMCPMC3090365
OpenAlexW2108941490

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.