Evidence map›Paper›PMID 21469953›Full record

ReviewAnnual review of biochemistry2011

Glycan microarrays for decoding the glycome.

Cory D Rillahan, James C Paulson

Abstract readReview
In one paragraph

Review in Annual review of biochemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 203 papers.

0numbers the graph read from it
0cells of the map it votes in
203citing papers in PubMed
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

203 citing papers in PubMed, 426 citations in OpenAlex.

  1. Humoral response to a viral glycan correlates with survival on PROSTVAC-VF.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Trial
  2. Trial
  3. Article
  4. Article
  5. Immunoproteomics: The Evolution from Classical Methods to Emerging Techniques.Methods in molecular biology (Clifton, N.J.) · 2026
    Review
  6. Use of Microbial Microarrays to Define Antibody Specificity.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  7. Article
  8. Article
  9. Article
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  12. Article
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  15. Cucurbit[8]uril-based supramolecular theranostics.Journal of nanobiotechnology · 2024
    Review
  16. Article
  17. Serum antibody screening using glycan arrays.Chemical Society reviews · 2024
    Review
  18. Article
  19. Article
  20. Article

143 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cory D RillahanDepartment of Chemical Physiology, The Scripps Research Institute, La Jolla, California 92037, USA. rillahan@scripps.edu
James C Paulson
Scripps Research Institute · US

Funding

Structural Basis of Immune Recognition of Glycosylated AntigensU54GM062116 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI BLIXT, OLA KLAS · 2001 to 2010
$80.3M
Viral and Host cDNA Libraries from 1918 Influenza CasesP01AI058113 · NIAID · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI GARCIA-SASTRE, ADOLFO · 2004 to 2010
$20.3M
MAMMALIAN SIALIC ACID BINDING PROTEINSR01GM060938 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI PAULSON, JAMES C · 2000 to 2010
$4.0M
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007606 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI NEMAZEE, DAVID · 1999 to 2013
$2.1M
In vivo targeting of hematopoetic cells with glycan ligands of siglecsR01CA138891 · NCI · SCRIPPS RESEARCH INSTITUTE, THE · PI PAULSON, JAMES C · 2010 to 2014
$1.9M
NCI NIH HHS R01 CA138891NIAID NIH HHS AI 007606NIAID NIH HHS AI058113NIAID NIH HHS P01 AI058113NIAID NIH HHS T32 AI007606NIGMS NIH HHS GM60938NIGMS NIH HHS GM62116NIGMS NIH HHS R01 GM060938NIGMS NIH HHS U54 GM062116
6 · The paper itself

Abstract

In the last decade, glycan microarrays have revolutionized the analysis of the specificity of glycan-binding proteins (GBPs), providing information that simultaneously illuminates the biology mediated by them and decodes the informational content of the glycome. Numerous methods have emerged for arraying glycans in a "chip" format, and glycan libraries have been assembled that address the diversity of the human glycome. Such arrays have been successfully used for analysis of GBPs, which mediate mammalian biology, host-pathogen interactions, and immune recognition of glycans relevant to vaccine production and cancer antigens. This review covers the development of glycan microarrays and applications that have provided insights into the roles of mammalian and microbial GBPs.

Indexed as

AnimalsCarbohydrate ConformationCarbohydrate SequenceGlycomicsHumansMicroarray AnalysisMolecular Sequence DataMolecular StructurePlant LectinsPolysaccharidesProtein BindingProteinsPlant LectinsPolysaccharidesProteins

Identifiers

PMID21469953
PMCPMC3116967
OpenAlexW2124539321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.