ArticleIndian pacing and electrophysiology journal2011
Initial experience of a cohort of patients with hypertrophic cardiomyopathy undergoing biventricular pacing.
Article in Indian pacing and electrophysiology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Cardiac pacing in patients with hypertrophic obstructive cardiomyopathy.Global cardiology science & practice · 2018Review
- Dyssynchronization reduces dynamic obstruction without affecting systolic function in patients with hypertrophic obstructive cardiomyopathy: a pilot study.The international journal of cardiovascular imaging · 2016Article
- Biventricular / left ventricular pacing in hypertrophic obstructive cardiomyopathy: an overview.Indian pacing and electrophysiology journal · 2012Article
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Authors and funding
5 authors.
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Abstract
backgroundDual chamber pacing improves functional status and reduces left ventricular outflow tract gradients in some, but not all patients with hypertrophic cardiomyopathy (HCM) by altering ventricular depolarisation. We investigated the use of biventricular (BIV) pacing in symptomatic patients with HCM.
method8 patients aged 58±7yrs with symptomatic HCM underwent BIV pacing. 5 patients had LVOT gradients >30mmHg. Ventricular electrodes were placed in the right ventricle (RV) and a branch of the coronary sinus. An atrial electrode was inserted to achieve BIV pacing with a short AV delay. The short-term effects of different pacing modalities were assessed using 2-D and Doppler echocardiography. Symptoms and exercise tolerance were assessed after a month of each pacing mode. Long-term follow up data was available for 5 years.
resultsBaseline EF was 67±14% and mean QRS duration was 132±26msecs. BIV pacing reduced QRS duration compared to RV pacing (129±46 vs. 205±54msecs, p<0.005). Five of the seven patients had baseline LVOT gradients (mean 67±25mmHg) that decreased to 41±15mm Hg with RV pacing (p<0.01) and 25±15mmHg with BIV pacing (p<0.005). Improvements in exercise time with active pacing occurred in six out of eight patients (75%), three (37.5%) had optimal exercise times with RV pacing and three with BIV pacing. Of the three patients with short term improvements with BIV pacing, one died 4 years post implant, one deteriorated with LV dilatation and one had the system explanted for infection.
conclusionBIV pacing showed short-term beneficial effects in some patients over and above RV pacing alone.
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21468273PMC3065748What OpenQuestion holds
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