Clamping the clamp of RNA polymerase.

Vladimir Svetlov, Evgeny Nudler

Abstract readComment

In one paragraph

Article in The EMBO journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it

0cells of the map it votes in

8citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

Origins and Molecular Evolution of the NusG Paralog RfaH.mBio · 2020
Article
Regulation of transcription elongation and termination.Biomolecules · 2015
Review
Ubiquitous transcription factors display structural plasticity and diverse functions: NusG proteins - Shifting shapes and paradigms.BioEssays : news and reviews in molecular, cellular and developmental biology · 2015
Review
NusG-Spt5 proteins-Universal tools for transcription modification and communication.Chemical reviews · 2013
Review
Interplay of DNA repair with transcription: from structures to mechanisms.Trends in biochemical sciences · 2012
Review
A nexus for gene expression-molecular mechanisms of Spt5 and NusG in the three domains of life.Journal of molecular biology · 2012
Review
The β subunit gate loop is required for RNA polymerase modification by RfaH and NusG.Molecular cell · 2011
Article
RNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.Nucleus (Austin, Tex.)
Review

4 · The record

Corrections and comments

Comment on
Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity.2011

5 · Who and what money

Authors and funding

2 authors.

Vladimir SvetlovDepartment of Biochemistry, New York University School of Medicine, New York, NY, USA.

Evgeny Nudler

Funding

Transcription Termination and its Regulation in E. coliR01GM058750 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NUDLER, EVGENY A · 1999 to 2014

$6.3M

NIGMS NIH HHS R01 GM058750NIGMS NIH HHS R01 GM58750

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ArchaeaChromosomal Proteins, Non-HistoneCrystallography, X-RayDNA-Directed RNA PolymerasesEscherichia coli ProteinsPeptide Elongation FactorsProtein Structure, QuaternaryTranscriptional Elongation FactorsTranscription FactorsChromosomal Proteins, Non-HistoneDNA-Directed RNA PolymerasesEscherichia coli ProteinsNusG protein, E coliPeptide Elongation FactorsSPT5 transcriptional elongation factorTranscriptional Elongation FactorsTranscription Factors

Identifiers

PMID21468097

DOI10.1038/emboj.2011.76

PMCPMC3094107

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.