ArticleGenetics2011
Wheat hybridization and polyploidization results in deregulation of small RNAs.
Article in Genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
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Who cites it
91 citing papers in PubMed, 202 citations in OpenAlex.
- Transposable elements and their epigenetic modifications mediate gene expression and subgenome dominance in Brassica carinata.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genome evolution through polyploidy: Enhancing plant stress resilience in agriculture.Proceedings of the National Academy of Sciences of the United States of America · 2026Review
- Small RNAs regulation and genomic harmony: insights into allopolyploid evolution in marsh orchids (Dactylorhiza).The New phytologist · 2026Article
- Gametocidal genes: biological mechanisms owing to hybrid dysgenesis in crop breeding, challenges and innovation.Annals of botany · 2026Review
- The molecular evolutionary basis of species formation revisited.Trends in genetics : TIG · 2025Review
- Characteristics and Molecular Mechanism of Slow Vegetative Growth in Hexaploid Transgenic Poplar 741 With an Insect-Resistance Gene.Plant biotechnology journal · 2025Article
- Article
- Transposon-Associated Small RNAs Involved in Plant Defense in Poplar.Plants (Basel, Switzerland) · 2025Article
- Translational Regulation of Duplicated Gene Expression Evolution in Allopolyploid Cotton.Genes · 2024Article
- Genomic prediction of synthetic hexaploid wheat upon tetraploid durum and diploid Aegilops parental pools.The plant genome · 2024Article
- Heritable changes of epialleles near genes in maize can be triggered in the absence of CHH methylation.Plant physiology · 2024Article
- Assessing small RNA profiles in potato diploid hybrid and its resynthesized allopolyploid reveals conserved abundance with distinct genomic distribution.Plant cell reports · 2024Article
- Enrichment and Diversification of the Wheat Genome via Alien Introgression.Plants (Basel, Switzerland) · 2024Review
- The Genomic Shock Hypothesis: Genetic and Epigenetic Alterations of Transposable Elements after Interspecific Hybridization in Plants.Epigenomes · 2023Review
- Epigenetic Regulation in Heterosis and Environmental Stress: The Challenge of Producing Hybrid Epigenomes to Face Climate Change.Epigenomes · 2023Review
- Multiple origins, one evolutionary trajectory: gradual evolution characterizes distinct lineages of allotetraploid Brachypodium.Genetics · 2023Article
- Recent allopolyploidy alters Spartina microRNA expression in response to xenobiotic-induced stress.Plant molecular biology · 2023Article
- Evolution and origin of bread wheat.The Plant cell · 2022Article
- Genomic and Meiotic Changes Accompanying Polyploidization.Plants (Basel, Switzerland) · 2022Review
- Retrotransposons: How the continuous evolutionary front shapes plant genomes for response to heat stress.Frontiers in plant science · 2022Review
31 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Speciation via interspecific or intergeneric hybridization and polyploidization triggers genomic responses involving genetic and epigenetic alterations. Such modifications may be induced by small RNAs, which affect key cellular processes, including gene expression, chromatin structure, cytosine methylation and transposable element (TE) activity. To date, the role of small RNAs in the context of wide hybridization and polyploidization has received little attention. In this work, we performed high-throughput sequencing of small RNAs of parental, intergeneric hybrid, and allopolyploid plants that mimic the genomic changes occurring during bread wheat speciation. We found that the percentage of small RNAs corresponding to miRNAs increased with ploidy level, while the percentage of siRNAs corresponding to TEs decreased. The abundance of most miRNA species was similar to midparent values in the hybrid, with some deviations, as seen in overrepresentation of miR168, in the allopolyploid. In contrast, the number of siRNAs corresponding to TEs strongly decreased upon allopolyploidization, but not upon hybridization. The reduction in corresponding siRNAs, together with decreased CpG methylation, as shown here for the Veju element, represent hallmarks of TE activation. TE-siRNA downregulation in the allopolyploid may contribute to genome destabilization at the initial stages of speciation. This phenomenon is reminiscent of hybrid dysgenesis in Drosophila.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.