ReviewJournal of cellular physiology2012
Cellular modeling of cancer invasion: integration of in silico and in vitro approaches.
Review in Journal of cellular physiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Next-generation osteosarcoma models for precision medicine.Communications biology · 2026Review
- Hybrid Class Balancing Approach for Chemical Compound Toxicity Prediction.Current computer-aided drug design · 2025Article
- Cancer cell sedimentation in 3D cultures reveals active migration regulated by self-generated gradients and adhesion sites.PLoS computational biology · 2024Article
- FromFrontiers in molecular biosciences · 2024Article
- Hybrid Cellular Automata Modeling Reveals the Effects of Glucose Gradients on Tumour Spheroid Growth.Cancers · 2023Article
- Integration of quantitative methods and mathematical approaches for the modeling of cancer cell proliferation dynamics.American journal of physiology. Cell physiology · 2023Review
- 3D cancer models: One step closer toFrontiers in immunology · 2023Review
- Heterotypic tumor models through freeform printing into photostabilized granular microgels.Biomaterials science · 2021Article
- A Lock Free Approach To Parallelize The Cellular Potts Model: Application To Ductal Carcinoma In Situ.Journal of integrative bioinformatics · 2020Article
- High-throughput cancer hypothesis testing with an integrated PhysiCell-EMEWS workflow.BMC bioinformatics · 2018Article
- Identification of genes associated with matrix metalloproteinases in invasive lung adenocarcinoma.Oncology letters · 2018Article
- Organotypic three-dimensional assays based on human leiomyoma-derived matrices.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018Review
- Combining radiation with hyperthermia: a multiscale model informed byJournal of the Royal Society, Interface · 2018Article
- The biology and mathematical modelling of glioma invasion: a review.Journal of the Royal Society, Interface · 2017Review
- Are Tumor Cell Lineages Solely Shaped by Mechanical Forces?Bulletin of mathematical biology · 2017Article
- Multiscale biphasic modelling of peritumoural collagen microstructure: The effect of tumour growth on permeability and fluid flow.PloS one · 2017Article
- Multiscale modelling of solid tumour growth: the effect of collagen micromechanics.Biomechanics and modeling in mechanobiology · 2016Article
- Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success.Annals of biomedical engineering · 2016Review
- Exosomal miRs in Lung Cancer: A Mathematical Model.PloS one · 2016Article
- Tumor growth prediction with reaction-diffusion and hyperelastic biomechanical model by physiological data fusion.Medical image analysis · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Cancer invasion is one of the hallmarks of cancer and a prerequisite for cancer metastasis. However, the invasive process is very complex, depending on multiple correlated intrinsic and environmental factors, and thus is difficult to study experimentally in a fully controlled way. Therefore, there is an increased demand for interdisciplinary integrated approaches combining laboratory experiments with multiscale in silico modeling. In this review, we will summarize current computational techniques applicable to model cancer invasion in silico, with a special focus on a class of individual-cell-based models developed in our laboratories. We also discuss their integration with traditional and novel in vitro experimentation, including new invasion assays whose design was inspired by computational modeling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.