Evidence map›Paper›PMID 21465223›Full record

ReviewCurrent gastroenterology reports2011

GERD-related cough: pathophysiology and diagnostic approach.

Jaclyn A Smith, Rayid Abdulqawi, Lesley A Houghton

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Diagnosis and treatment of gastroesophageal reflux disease.World journal of gastrointestinal pharmacology and therapeutics · 2014
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Jaclyn A SmithRespiratory Research Group, University of Manchester, ERC Building, Second Floor, Wythenshawe Hospital, Manchester M23 9LT, UK. jacky.smith@manchester.ac.uk
Rayid Abdulqawi
Lesley A Houghton
Mayo Clinic in Florida · USNIHR Manchester Biomedical Research Centre · GBWythenshawe Hospital · GB

Funding

Medical Research Council G0701918
6 · The paper itself

Abstract

Chronic cough is a common problem resulting in significant impairment of quality of life. Along with cough variant asthma and nasal disease, gastroesophageal reflux is considered one of three main causes of cough. Despite this, acid suppression therapy is often far from effective. This review aims to explore whether reflux can lead to cough, the circumstances in which this is most likely to occur, and the potential mechanisms linking these processes. Particular mechanisms to be explored include laryngopharyngeal reflux, microaspiration, and neuronal cross-organ sensitization. Finally, diagnostic approaches are considered.

Indexed as

Chronic DiseaseCoughElectric ImpedanceEsophageal pH MonitoringEsophagoscopyEsophagusGastroesophageal RefluxHumansRespiratory Aspiration

Identifiers

PMID21465223
OpenAlexW2150840188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.