Trial reportArchives of pediatrics & adolescent medicine2011
A randomized controlled trial of home injury hazard reduction: the HOME injury study.
Trial report in Archives of pediatrics & adolescent medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00129324 (Neurobehavioral Effects of Prevalent Neurotoxicants in Children), which is not on this map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurobehavioral Effects of Prevalent Neurotoxicants in Children: A Cohort Study of the Cincinnati Center for Children's Environmental Health
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Preventing childhood scalds within the home: Overview of systematic reviews and a systematic review of primary studies.Burns : journal of the International Society for Burn Injuries · 2015Pooled it
- Home safety education and provision of safety equipment for injury prevention.The Cochrane database of systematic reviews · 2012Pooled it
- Lowering Urinary Phthalate Metabolite Concentrations among Children by Reducing Contaminated Dust in Housing Units: A Randomized Controlled Trial and Observational Study.Environmental science & technology · 2020Trial
- Effect of Residential Lead-Hazard Interventions on Childhood Blood Lead Concentrations and Neurobehavioral Outcomes: A Randomized Clinical Trial.JAMA pediatrics · 2018Trial
- A randomised safety promotion intervention trial among low-income families with toddlers.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2018Trial
- Lessons learned from longitudinal biomonitoring and birth cohort studies: informing the future of reproductive health research in Canada.Environmental health : a global access science source · 2026Article
- Development and validation of a new instrument to assess risk of falls among infants and toddlers.BMC public health · 2026Article
- Burns in Early Childhood: Age-Specific Causes, Risks, Management, and Implications-A Narrative Review.Children (Basel, Switzerland) · 2025Review
- Voices from the Ground: Community Perspectives on Preventing Unintentional Child Injuries in Low-Income Settings.International journal of environmental research and public health · 2024Article
- Effectiveness of systematically delivered evidence-based home safety promotion to improve child home safety practices: a controlled before-and-after study.Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention · 2023Article
- Injuries of Primary School Children during Sports Activities.Zdravstveno varstvo · 2023Article
- Keeping our children safe: piloting a hospital-based home-visitation program in Israel.Israel journal of health policy research · 2022Article
- Identifying periods of heightened susceptibility to lead exposure in relation to behavioral problems.Journal of exposure science & environmental epidemiology · 2022Article
- Impact of the national home safety equipment scheme 'Safe At Home' on hospital admissions for unintentional injury in children under 5: a controlled interrupted time series analysis.Journal of epidemiology and community health · 2022Article
- Residential dust lead levels and the risk of childhood lead poisoning in United States children.Pediatric research · 2021Article
- Factors Associated With Residential Relocation and Effects on Early Childhood Development in a Low-Income Home Visitation Population.The journal of primary prevention · 2021Article
- Effect of lock boxes and education on safe storage of medications.Injury epidemiology · 2020Article
- Evaluation of a mobile safety center's impact on pediatric home safety knowledge and device use.Injury epidemiology · 2020Article
- Adolescent follow-up in the Health Outcomes and Measures of the Environment (HOME) Study: cohort profile.BMJ open · 2020Article
- Factors associated with injuries among preschool children in Egypt: demographic and health survey results, 2014.BMC public health · 2020Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
objectiveTo test the efficacy of installing safety devices in the homes of young children on total injury rates and on injuries deemed a priori modifiable by the installation of these devices.
designA nested, prospective, randomized controlled trial.
settingIndoor environment of housing units.
participantsMothers and their children from birth to 3 years old participating in the Home Observation and Measures of the Environment study. Among 8878 prenatal patients, 1263 (14.2%) were eligible, 413 (32.7%) agreed to participate, and 355 were randomly assigned to the intervention (n = 181) or control (n = 174) groups.
interventionInstallation of multiple passive measures (eg, stair gates, cabinet locks, and smoke detectors) to reduce exposure to injury hazards. Injury hazards were assessed at home visits by teams of trained research assistants using a validated survey.
main outcome measureModifiable and medically attended injury (ie, telephone calls, office visits, and emergency visits for injury).
resultsThe mean age of children at intervention was 6.3 months. Injury hazards were reduced in the intervention homes but not in the control homes at 1 and 2 years (P < .004). There was no difference in the rate for all medically attended injuries in intervention children compared with controls: 14.3 injuries (95% confidence interval [CI], 9.7-21.1 injuries) vs 20.8 injuries (95% CI, 14.4-29.9 injuries) per 100 child-years (P = .17); but there was a significant reduction in the rate of modifiable medically attended injuries in intervention children compared with controls: 2.3 injuries (95% CI, 1.0-5.5 injuries) vs 7.7 injuries (95% CI, 4.2-14.2 injuries) per 100 child-years (P = .03).
conclusionAn intervention to reduce exposure to hazards in homes led to a 70% reduction in the rate of modifiable medically attended injury.
trial registrationclinicaltrials.gov Identifier: NCT00129324.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.