ArticleJournal of the American Chemical Society2011
Controlling and switching the morphology of micellar nanoparticles with enzymes.
Article in Journal of the American Chemical Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed.
- Cascade Mesophase Transitions of Multi-enzyme Responsive Polymeric Formulations.Biomacromolecules · 2024Article
- Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems.Chemical reviews · 2024Review
- Structural Determinants of Stimuli-Responsiveness in Amphiphilic Macromolecular Nano-assemblies.Progress in polymer science · 2024Article
- Architecture-Based Programming of Polymeric Micelles to Undergo Sequential Mesophase Transitions.ACS macro letters · 2023Article
- Polymeric Micelles for Breast Cancer Therapy: Recent Updates, Clinical Translation and Regulatory Considerations.Pharmaceutics · 2022Review
- Local detection of pH-induced disaggregation of biocompatible micelles by fluorescence switch ON.Chemical science · 2022Article
- Automation and data-driven design of polymer therapeutics.Advanced drug delivery reviews · 2021Review
- High efficiency loading of micellar nanoparticles with a light switch for enzyme-induced rapid release of cargo.Biomaterials science · 2021Article
- Synthesis of Complex Molecular Systems-The Foreseen Role of Organic Chemists.ACS central science · 2020Article
- Assessing the range of enzymatic and oxidative tunability for biosensor design.Journal of materials chemistry. B · 2020Review
- Size-Tunable Strategies for a Tumor Targeted Drug Delivery System.ACS central science · 2020Review
- Poly(peptide): Synthesis, Structure, and Function of Peptide-Polymer Amphiphiles and Protein-like Polymers.Accounts of chemical research · 2020Article
- Synthesis of crosslinkable diblock terpolymers PDPA-RSC advances · 2019Article
- Selective inhibition of cancer cells by enzyme-induced gain of function of phosphorylated melittin analogues.Chemical science · 2017Article
- Stimulus-responsive block copolymer nano-objects and hydrogelsPolymer chemistry · 2017Article
- Non-equilibrium steady states in supramolecular polymerization.Nature communications · 2017Article
- Using Dynamic Covalent Chemistry To Drive Morphological Transitions: Controlled Release of Encapsulated Nanoparticles from Block Copolymer Vesicles.Journal of the American Chemical Society · 2017Article
- Protease-Sensitive Nanomaterials for Cancer Therapeutics and Imaging.Industrial & engineering chemistry research · 2017Review
- Stimuli-Regulated Smart Polymeric Systems for Gene Therapy.Polymers · 2017Review
- Responsive Hybrid (Poly)peptide-Polymer Conjugates.Journal of materials chemistry. B · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Micelles were prepared from polymer-peptide block copolymer amphiphiles containing substrates for protein kinase A, protein phosphatase-1, and matrix metalloproteinases 2 and 9. We examine reversible switching of the morphology of these micelles through a phosphorylation-dephosphorylation cycle and study peptide-sequence directed changes in morphology in response to proteolysis. Furthermore, the exceptional uniformity of these polymer-peptide particles makes them amenable to cryo-TEM reconstruction techniques lending insight into their internal structure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.