ArticleAmerican journal of primatology2011
Early social experience affects behavioral and physiological responsiveness to stressful conditions in infant rhesus macaques (Macaca mulatta).
Article in American journal of primatology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
27 citing papers in PubMed, 40 citations in OpenAlex.
- A Comparative Analysis of the Genetic Structures of Rhesus Macaques (Macaca mulatta) Kept in Enclosure-Based Systems and Semi-Natural Settings.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Rhesus infant nervous temperament predicts peri-adolescent central amygdala metabolism & behavioral inhibition measured by a machine-learning approach.Translational psychiatry · 2024Article
- Emotional responses in monkeys differ depending on the stimulus type, sex, and neonatal amygdala lesion status.Behavioral neuroscience · 2020Article
- Maternal and Breast Milk Influences on the Infant Gut Microbiome, Enteric Health and Growth Outcomes of Rhesus Monkeys.Journal of pediatric gastroenterology and nutrition · 2019Article
- Hair cortisol and stable carbon and nitrogen isotope ratios in barbary macaques (Macaca sylvanus) from Gibraltar.Rapid communications in mass spectrometry : RCM · 2019Article
- Mechanisms of network evolution: a focus on socioecological factors, intermediary mechanisms, and selection pressures.Primates; journal of primatology · 2019Review
- Early amygdala damage alters the way rhesus macaques process species-specific audio-visual vocalizations.Behavioral neuroscience · 2019Article
- Coping style and cortisol levels in infancy predict hair cortisol following new group formation in captive rhesus macaques (Macaca mulatta).American journal of primatology · 2018Article
- Intermittent pair-housing, pair relationship qualities, and HPA activity in adult female rhesus macaques.American journal of primatology · 2018Article
- Longitudinal Anthropometric Assessment of Rhesus Macaque (Comparative medicine · 2018Article
- Naturally Occurring Nonhuman Primate Models of Psychosocial Processes.ILAR journal · 2017Review
- Neonatal perirhinal cortex lesions impair monkeys' ability to modulate their emotional responses.Behavioral neuroscience · 2017Article
- An MRI study of the corpus callosum in monkeys: Developmental trajectories and effects of neonatal hippocampal and amygdala lesions.Developmental psychobiology · 2017Article
- Increased anxiety-like behaviors, but blunted cortisol stress response after neonatal hippocampal lesions in monkeys.Psychoneuroendocrinology · 2017Article
- Consequences of early adverse rearing experience(EARE) on development: insights from non-human primate studies.Zoological research · 2017Review
- Laboratory rhesus macaque social housing and social changes: Implications for research.American journal of primatology · 2017Review
- Increased irritability, anxiety, and immune reactivity in transgenic Huntington's disease monkeys.Brain, behavior, and immunity · 2016Article
- Effect of Indoor Compared with Outdoor Location during Gestation on the Incidence of Diarrhea in Indoor-Reared Rhesus Macaques (Macaca mulatta).Journal of the American Association for Laboratory Animal Science : JAALAS · 2016Article
- Addressing the Complexity of Tourette's Syndrome through the Use of Animal Models.Frontiers in neuroscience · 2016Review
- Videotaped behavior as a predictor of clinical outcome in rhesus macaques (Macaca mulatta).Comparative medicine · 2014Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Studies on early development have demonstrated the profound effects of early social experience on the behavioral development and physiology of young rhesus macaques. Given these relationships, we hypothesized that rhesus macaques exposed to different nursery-rearing conditions may develop unique biobehavioral profiles. If this is true, the assessment of temperament may allow us to pinpoint successful rearing environments, thus improving the overall health of nonhuman primates that are raised in captive environments. We conducted biobehavioral assessments in order to examine differences in the development of infants raised under four different peer-rearing conditions (continuous pairing (CP), intermittent pairing, CP with partner rotation, and intermittent rotational pairing) and compared these animals with data from a mother-reared control group. Overall, continuous rotationally paired animals were most similar to mother-reared controls on most behavioral and temperament measures, suggesting that more socially complex rearing environments (greater number of social partners) favor a more active behavioral style. Cortisol profiles of mother-reared controls were similar to both CP groups, and these three groups had higher cortisol concentrations than the intermittent rotational-pairing group. In addition, intermittently paired infants displayed a significantly higher frequency of self-stroke behavior during a human intruder challenge, an abnormal behavior also known as floating limb which has been shown to be a precursor of self-biting. Overall, the data are consistent with the idea that social complexity in the nursery, as operationalized in our continuous rotational pairing, leads to a biobehavioral profile that is most similar to that of infants raised by their mothers in large, socially complex, cages.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.