Evidence map›Paper›PMID 21462168›Full record

ArticleCurrent protocols in immunology2011

Infection of mice with Francisella as an immunological model.

J Wayne Conlan, Wangxue Chen, Catharine M Bosio, Siobhán C Cowley, Karen L Elkins

Abstract read
In one paragraph

Article in Current protocols in immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Article
  3. Frontiers in microbiology · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Deletion Mutants ofPathogens (Basel, Switzerland) · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Virulence ofMicroorganisms · 2020
    Article
  13. Article
  14. Innate Immune Recognition: An Issue More Complex Than Expected.Frontiers in cellular and infection microbiology · 2019
    Review
  15. Article
  16. Article
  17. Article
  18. F. novicida-Infected A. castellanii Does Not Enhance Bacterial Virulence in Mice.Frontiers in cellular and infection microbiology · 2016
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J Wayne ConlanNational Research Council of Canada, Institute for Biological Sciences, Ottawa, Ontario, Canada.
Wangxue Chen
Catharine M Bosio
Siobhán C Cowley
Karen L Elkins

Funding

Immunity to Pulmonary InfectionsZIAAI001013 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BOSIO, CATHARINE · 2009 to 2025
$18.9M
Intramural NIH HHS ZIA AI001013
6 · The paper itself

Abstract

This unit describes the utility of various mouse models of infection for studying pathogenesis and adaptive immune responses to the facultative intracellular bacteria pathogen Francisella tularensis. By judicious use of different combinations of mouse and bacterial strains, as well as different routes of infection, murine tularemia models may be used to explore a complete picture of F. tularensis infection and immunity. Moreover, studies using Francisella, particularly the Live Vaccine Strain (LVS), serve as a convenient and tractable model system that appears to be representative of mammalian host responses to intracellular pathogens in general.

Indexed as

Disease Models, AnimalAnimalsAnimal StructuresBacteremiaBacteriological TechniquesEar AuricleFrancisella tularensisGastrointestinal TractImmunologic TechniquesMiceMice, Inbred StrainsMuscle, SkeletalPeritoneal CavityRespiratory Tract InfectionsSkin Diseases, BacterialTularemia

Identifiers

PMID21462168
PMCPMC3405980

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.