Evidence map›Paper›PMID 21461953›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2011

Comparison and correlates of three preference-based health-related quality-of-life measures among overweight and obese women with urinary incontinence.

Angela Marinilli Pinto, Miriam Kuppermann, Sanae Nakagawa, Eric Vittinghoff, Rena R Wing, John W Kusek, William H Herman, Leslee L Subak

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Lifestyle interventions for the treatment of urinary incontinence in adults.The Cochrane database of systematic reviews · 2015
    Pooled it
  2. Trial
  3. Trial
  4. The effect of weight loss on changes in health-related quality of life among overweight and obese women with urinary incontinence.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2012
    Trial
  5. Article
  6. Article
  7. The validity and responsiveness of the ICECAP-A capability-well-being measure in women with irritative lower urinary tract symptoms.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2016
    Article
  8. Article
  9. Article
  10. Bodyweight, gender, and quality of life: a population-based longitudinal study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Angela Marinilli PintoDepartment of Psychology, Baruch College, CUNY, 55 Lexington Avenue, B8-215, New York, NY 10010, USA. Angela.Pinto@baruch.cuny.edu
Miriam Kuppermann
Sanae Nakagawa
Eric Vittinghoff
Rena R Wing
John W Kusek
William H Herman
Leslee L Subak
University of California, San Francisco · USBaruch College · USBrown University · USNational Institute of Diabetes and Digestive and Kidney Diseases · USUniversity of Michigan–Ann Arbor · US

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Weight Reduction for Incontinence Network(WIN)U01DK067860 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRADY, DEBORAH G · 2003 to 2007
$2.3M
Weight Reduction for Incontinence NetworkU01DK067861 · NIDDK · MIRIAM HOSPITAL · PI WING, RENA R · 2003 to 2007
$2.2M
Weight Reduction for Incontinence Network (WIN)U01DK067862 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FRANKLIN, FRANK A · 2003 to 2007
$1.7M
Patient Oriented Research and Mentoring in Obesity and Urinary IncontinenceK24DK080775 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SUBAK, LESLEE L · 2008 to 2019
$1.7M
Managing obesity by combining behavioral weight loss and commercial approachesK23DK075645 · NIDDK · BERNARD M. BARUCH COLLEGE · PI PINTO, ANGELA MARINILLI · 2007 to 2010
$640k
NIDDK NIH HHS 5K23DK075645NIDDK NIH HHS AU01 DK067862NIDDK NIH HHS K23 DK075645NIDDK NIH HHS K24 DK080775NIDDK NIH HHS P30 DK092926NIDDK NIH HHS #U01 DK067860NIDDK NIH HHS U01 DK067860NIDDK NIH HHS U01 DK067861NIDDK NIH HHS U01DK067861NIDDK NIH HHS U01 DK067862
6 · The paper itself

Abstract

purposeTo compare three preference-based health-related quality-of-life (HRQL) measures and examine independent correlates of HRQL among overweight and obese women with urinary incontinence (UI) enrolled in a weight loss intervention trial.

methodsParticipants completed baseline questionnaires, which included the Health Utilities Index 3 (HUI3) and Medical Outcomes Study Short Form-36 (SF-36). The SF-36 was used to derive SF-6D and estimated Quality of Well-Being (eQWB) scores. Height, weight, medical history, incontinence measures, and level of physical activity also were assessed. The intraclass correlation coefficient (ICC) was computed, and differences in mean scores across HRQL measures were examined. Potential correlates of HUI3, SF-6D, and eQWB scores were evaluated using multivariable generalized linear models.

resultsMean ± SD scores for the HUI3, SF-6D, and eQWB were 0.81 ± 0.18, 0.75 ± 0.10, and 0.71 ± 0.06, respectively. Significant differences were observed across measures (P < 0.0001), and the overall ICC was 0.36. In multivariable analyses, BMI was negatively associated with HUI3 (P = 0.003) and eQWB (P < 0.001), and UI episode frequency was negatively associated with eQWB (P = 0.015) and SF-6D (P < 0.001).

conclusionsSignificant differences in mean utilities across the HUI3, SF-6D, and eQWB indicate that these measures do not assess identical dimensions of HRQL. Both BMI and UI episode frequency were related to HRQL in this cohort; however, the magnitude of the relationship depended on the preference-based measure used. These findings highlight the need to consider the method used to generate HRQL values for calculating quality-adjusted life-years in cost-utility analyses, since choice of method may have a substantial impact on the outcome of the analysis.

Indexed as

Sickness Impact ProfileAlabamaBehavior TherapyBody Mass IndexComorbidityFemaleHumansMiddle AgedObesityQuality-Adjusted Life YearsReproducibility of ResultsRhode IslandUrinary IncontinenceWeight Reduction Programs

Identifiers

PMID21461953
PMCPMC3174313
OpenAlexW2050234423

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.