ArticleEcotoxicology (London, England)2011
Fitness costs of resistance to Bti toxins in the dengue vector Aedes aegypti.
Article in Ecotoxicology (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
28 citing papers in PubMed, 72 citations in OpenAlex.
- Pollution-Driven Selection in a Non-Biting Midge: Genome-Wide Responses to Bacillus thuringiensis israelensis and Copper.Molecular ecology · 2026Article
- Aedes aegypti strain selected with Bacillus thuringiensis svar. israelensis larvicide for 50 generations remains susceptible and exhibited increased fitness.Parasites & vectors · 2025Article
- Temporal genomics in Hawaiian crickets reveals compensatory intragenomic coadaptation during adaptive evolution.Nature communications · 2024Article
- Challenge and opportunity for vector control strategies on key mosquito-borne diseases during the COVID-19 pandemic.Frontiers in public health · 2023Review
- Article
- Brazilian Populations ofViruses · 2022Article
- Genetic Stability and Fitness ofFrontiers in bioengineering and biotechnology · 2022Article
- Biochemical characterization of Aedes aegypti (Linnaeus) (Diptera: Culicidae) resistance to deltamethrin, fipronil, and imidacloprid.Environmental monitoring and assessment · 2021Article
- Effects of Selection to Diflubenzuron andInsects · 2021Article
- Aedes aegypti continuously exposed to Bacillus thuringiensis svar. israelensis does not exhibit changes in life traits but displays increased susceptibility for Zika virus.Parasites & vectors · 2021Article
- Review
- Short-Term Selection to Diflubenzuron andInsects · 2021Article
- Long-term exposure of Aedes aegypti to Bacillus thuringiensis svar. israelensis did not involve altered susceptibility to this microbial larvicide or to other control agents.Parasites & vectors · 2018Article
- Larval Exposure to the Bacterial InsecticideInsects · 2018Article
- Mosquito Microbiome Dynamics, a Background for Prevalence and Seasonality of West Nile Virus.Frontiers in microbiology · 2017Article
- Immuno-physiological adaptations confer wax moth Galleria mellonella resistance to Bacillus thuringiensis.Virulence · 2016Article
- Transstadial Effects of Bti on Traits of Aedes aegypti and Infection with Dengue Virus.PLoS neglected tropical diseases · 2016Article
- Fitness cost in field and laboratory Aedes aegypti populations associated with resistance to the insecticide temephos.Parasites & vectors · 2015Article
- Article
- Chemical and biological insecticides select distinct gene expression patterns in Aedes aegypti mosquito.Biology letters · 2014Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sustainable insect vector disease control strategies involve delaying the evolution of resistance to insecticides in natural populations. The evolutionary dynamics of resistance in the field is highly dependent on the fitness cost of resistance alleles. To successfully manage resistance evolution in target species, it is not only important to find evidence of fitness cost in resistant insects, but also to determine at which stage of the insect's life it is expressed. Here, we show that resistance costs to the bacterio-insecticide Bacillus thuringiensis subsp. israelensis (Bti) are expressed at all the life-stages of the dengue vector Aedes aegypti, including egg survival, larval development time, and female fecundity. We show that the storage of eggs for 4 months is long enough to counter-select resistance alleles. This suggests that Bti resistance is not likely to evolve in temperate climates where most mosquito species overwinter as eggs. In tropical regions with a rapid turn-over of generations, resistance alleles are likely to be counter-selected in only few generations without treatment through fitness costs expressed in terms of larval development time and female fecundity. We discuss the implications of our findings in terms of sustainable management strategies in light of the challenge of preserving the long-term efficiency of this environmentally safe anti-mosquito bio-insecticide.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.