ArticleInternal and emergency medicine2011
Residual emboli on lung perfusion scan or multidetector computed tomography after a first episode of acute pulmonary embolism.
Article in Internal and emergency medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Study on the Clinical Course Of Pulmonary Embolism
An Observational Cohort Study to Validate SEARCH, a Novel Hierarchical Algorithm to Define Long-term Outcomes After Pulmonary Embolism
Who cites it
26 citing papers in PubMed, 71 citations in OpenAlex.
- CIRSE Standards of Practice on Endovascular Treatment of Acute Pulmonary Embolism.Cardiovascular and interventional radiology · 2026Article
- Deep learning-based identification of chronic pulmonary embolism on CTPA: a regional lung analysis using multiplanar MIP images.European radiology experimental · 2026Article
- Post-Pulmonary Embolism Syndrome: New Phenotypes Come into Focus.Journal of clinical medicine · 2026Review
- CIRSE Standards of Practice on Endovascular Treatment of Acute Pulmonary Embolism.Cardiovascular and interventional radiology · 2025Article
- How I treat pediatric pulmonary embolism.Blood · 2025Review
- Comprehensive review of pulmonary embolism imaging: past, present and future innovations in computed tomography (CT) and other diagnostic techniques.Japanese journal of radiology · 2025Review
- The Aftermath of Pulmonary Embolism: Are Residual Thrombi Clinically Significant?Diagnostics (Basel, Switzerland) · 2025Review
- Long-term sequelae following acute pulmonary embolism: A nationwide follow-up study regarding the incidence of CTEPH, dyspnea, echocardiographic and V/Q scan abnormalities.Pulmonary circulation · 2023Article
- Observational cohort study to validate SEARCH, a novel hierarchical algorithm to define long-term outcomes after pulmonary embolism.BMJ open · 2023Observational
- Review
- Clinical and imaging risk factors for the persistence of thromboembolism following acute pulmonary embolism.Quantitative imaging in medicine and surgery · 2022Article
- Usefulness of a refined computed tomography imaging method to assess the prevalence of residual pulmonary thrombi in patients 1 year after acute pulmonary embolism: The Nagoya PE study.Journal of thrombosis and haemostasis : JTH · 2022Article
- Performance of a 3D convolutional neural network in the detection of hypoperfusion at CT pulmonary angiography in patients with chronic pulmonary embolism: a feasibility study.European radiology experimental · 2021Article
- Incidence of residual perfusion defects by lung scintigraphy in patients treated with rivaroxaban compared with warfarin for acute pulmonary embolism.Journal of thrombosis and thrombolysis · 2020Article
- Quality of life and functional limitations after pulmonary embolism and its prognostic relevance.Journal of thrombosis and haemostasis : JTH · 2019Article
- EANM guideline for ventilation/perfusion single-photon emission computed tomography (SPECT) for diagnosis of pulmonary embolism and beyond.European journal of nuclear medicine and molecular imaging · 2019Article
- Prevalence of antiphospholipid antibodies among patients with chronic thromboembolic pulmonary hypertension.Internal and emergency medicine · 2019Article
- Serial imaging after pulmonary embolism and correlation with functional limitation at 12 months: Results of the ELOPE Study.Research and practice in thrombosis and haemostasis · 2018Article
- Epidemiology, Pathophysiology, and Natural History of Pulmonary Embolism.Seminars in interventional radiology · 2018Review
- Can thrombus age guide thrombolytic therapy?Cardiovascular diagnosis and therapy · 2017Review
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The rate of resolution of a first episode of pulmonary embolism (PE) is uncertain. A baseline test indicating any residual PE is pivotal in aiding a more accurate diagnosis of recurrent PE. This study aimed to assess the rate and risk factors of residual PE with either multidetector computed tomography imaging (MDCT) or lung perfusion scan (LPS) using a cross-sectional study in which consecutive patients were enrolled with a first objectively documented episode of symptomatic PE, and who were considered for possible treatment withdrawal after at least 3 months of anticoagulation. A first cohort of patients (n = 80) underwent MDCT, while the subsequent cohort (n = 93) underwent LPS. The two cohorts had similar characteristics, and 98.3% of patients had non high-risk index PE. MDCT detected residual PE in 15% of subjects (12/80, 95% CI 8-25%) after a mean of 9 months of anticoagulation. No clinical characteristics were significantly associated with residual PE at MDCT. LPS detected residual PE in 28% (26/93, 95% CI 19-38%) of patients after a period of a mean of 9 months of anticoagulation with a significant association with increasing age and known pulmonary disease. Resolution of PE was high after a first episode of non high-risk PE treated with heparin followed by at least 3 months of anticoagulation. Age and coexistent pulmonary disease influence the presence of residual PE detected by LPS, but not by MDCT. Further studies are warranted in which the presence of residual embolism is detected by repetition of the same test that had been initially carried out.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.