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ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2011

Clinical and microbiological characteristics of infections caused by various Nocardia species in Taiwan: a multicenter study from 1998 to 2010.

W L Liu, C C Lai, W C Ko, Y H Chen, H J Tang, Y L Huang, Y T Huang, P R Hsueh

Abstract readMulticenter Study
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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Clinical and microbiological characteristics of Nocardia infections: a 10-Year multicentre study from Türkiye.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Review
  3. Clinical characteristics and drug resistance of Nocardia in Henan, China, 2017-2023.Annals of clinical microbiology and antimicrobials · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Epidemiology ofAntibiotics (Basel, Switzerland) · 2022
    Article
  8. Article
  9. Case Report: Disseminated Nocardiosis Caused byFrontiers in public health · 2022
    Article
  10. Brain sciences · 2021
    Article
  11. Assessment of VITEK® MS IVD database V3.0 for identification of Nocardia spp. using two culture media and comparing direct smear and protein extraction procedures.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  12. Observational
  13. Review
  14. Primary Cutaneous Nocardiosis Caused byAnnals of dermatology · 2017
    Article
  15. Frontiers in cellular and infection microbiology · 2017
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

W L LiuDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan.
C C Lai
W C Ko
Y H Chen
H J Tang
Y L Huang
Y T Huang
P R Hsueh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This multicenter study in Taiwan investigated the clinical presentations of various Nocardia species infections based on 16S rRNA sequence analysis. Patients with nocardiosis in four large medical centers from 1998 to 2010 were included. A total of 100 preserved nonduplicate isolates causing human infection were identified as Nocardia species. Sequencing analysis of 16S rRNA confirmed that 35 of 36 N. asteroides isolates identified by conventional tests were non-asteroides Nocardia species, and that two of 50 N. brasiliensis isolates had also been initially misidentified. N. brasiliensis (50%) was the most common pathogen, followed by N. cyriacigeorgica (18%). In addition, several rare pathogens were identified, including N. asiatica, N. rhamnosiphila, N. abscessus, N. transvalensis, N. elegans, and N. carnea. Primary cutaneous infection was the most common presentation, noted in 55 (55%) patients, while pulmonary infection presented in 26 (26%) patients. The crude mortality rate was 6.7% (6/89), and was lowest for primary cutaneous infection (2.2%) and highest for disseminated disease and pulmonary infection (16.7%). In conclusion, N. brasiliensis and N. cyriacigeorgica were the most common pathogens causing nocardiosis in Taiwan. Molecular methods for identifying Nocardia to the species level are mandatory for better understanding the epidemiology and clinical characteristics of patients with nocardiosis.

Indexed as

AdultAgedAnti-Infective AgentsBase SequenceDemographyDNA, BacterialDNA, RibosomalDrug CombinationsFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMolecular Sequence DataNocardiaNocardia InfectionsAnti-Infective AgentsDNA, BacterialDNA, RibosomalDrug CombinationsRNA, Ribosomal, 16STrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.