ArticleMaterials science & engineering. C, Materials for biological applications2009
Trabecular scaffolds created using micro CT guided fused deposition modeling.
Article in Materials science & engineering. C, Materials for biological applications, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 124 citations in OpenAlex.
- Experimental Framework for the Setup and Validation of Individualized Bone Conduction Hearing Computational Models.Biomimetics (Basel, Switzerland) · 2025Article
- Integrating Melt Electrowriting and Fused Deposition Modeling to Fabricate Hybrid Scaffolds Supportive of Accelerated Bone Regeneration.Advanced healthcare materials · 2024Article
- Studying trabecular bone samples demonstrates a power law relation between deteriorated structure and mechanical properties - a study combining 3D printing with the finite element method.Frontiers in endocrinology · 2023Article
- 3D printed trabeculae conditionally reproduce the mechanical properties of the actual trabeculae - A preliminary study.Heliyon · 2022Article
- Article
- Three-Dimensional Printed Lightweight Composite Foams.ACS omega · 2020Article
- Article
- Additive manufacturing of bone scaffolds.International journal of bioprinting · 2019Review
- Additive Manufacturing for Guided Bone Regeneration: A Perspective for Alveolar Ridge Augmentation.International journal of molecular sciences · 2018Review
- Dual Porosity Protein-based Scaffolds with Enhanced Cell Infiltration and Proliferation.Scientific reports · 2018Article
- A novel use of 3D printing model demonstrates the effects of deteriorated trabecular bone structure on bone stiffness and strength.Journal of the mechanical behavior of biomedical materials · 2018Article
- Review of additive manufactured tissue engineering scaffolds: relationship between geometry and performance.Burns & trauma · 2018Review
- Process-induced degradation of bioresorbable PDLGA in bone tissue scaffold production.Journal of materials science. Materials in medicine · 2017Article
- Solid Freeform Techniques Application in Bone Tissue Engineering for Scaffold Fabrication.Tissue engineering and regenerative medicine · 2017Article
- Designing Biomaterials for 3D Printing.ACS biomaterials science & engineering · 2016Article
- Automating the processing steps for obtaining bone tissue-engineered substitutes: from imaging tools to bioreactors.Tissue engineering. Part B, Reviews · 2014Review
- Anatomic changes in the macroscopic morphology and microarchitecture of denervated long bone tissue after spinal cord injury in rats.BioMed research international · 2014Article
- A novel biomimetic polymer scaffold design enhances bone ingrowth.Journal of biomedical materials research. Part A · 2009Article
- A handheld computer as part of a portable in vivo knee joint load monitoring system.Journal of medical devices · 2008Article
- Sensate scaffolds can reliably detect joint loading.Journal of biomedical materials research. Part B, Applied biomaterials · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Free form fabrication and high resolution imaging techniques enable the creation of biomimetic tissue engineering scaffolds. A 3D CAD model of canine trabecular bone was produced via micro CT and exported to a fused deposition modeler, to produce polybutylene terephthalate (PBT) trabeculated scaffolds and four other scaffold groups of varying pore structures. The five scaffold groups were divided into subgroups (n=6) and compression tested at two load rates (49 N/s and 294 N/s). Two groups were soaked in a 25 °C saline solution for 7 days before compression testing. Micro CT was used to compare porosity, connectivity density, and trabecular separation of each scaffold type to a canine trabecular bone sample. At 49 N/s the dry trabecular scaffolds had a compressive stiffness of 4.94±1.19 MPa, similar to the simple linear small pore scaffolds and significantly more stiff (p<0.05) than either of the complex interconnected pore scaffolds. At 294 N/s, the compressive stiffness values for all five groups roughly doubled. Soaking in saline had an insignificant effect on stiffness. The trabecular scaffolds matched bone samples in porosity; however, achieving physiologic connectivity density and trabecular separation will require further refining of scaffold processing.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.