ArticleNeuroscience2011
Hippocampal inputs mediate theta-related plasticity in anterior thalamus.
Article in Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- A role for the fornix in temporal sequence memory.The European journal of neuroscience · 2023Article
- Time to retire the serial Papez circuit: Implications for space, memory, and attention.Neuroscience and biobehavioral reviews · 2022Review
- The anterior thalamic nuclei: core components of a tripartite episodic memory system.Nature reviews. Neuroscience · 2022Review
- Hippocampal atrophy and quantitative EEG markers in mild cognitive impairment in temporal lobe epilepsy versus extra-temporal lobe epilepsy.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Theta-gamma coupling as a cortical biomarker of brain-computer interface-mediated motor recovery in chronic stroke.Brain communications · 2022Article
- Implementation of Imaging Methods in Evaluation of T2DM-Correlated Brain Alterations and Cognitive Dysfunction.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020Review
- Cerebral perfusion mapping during retrieval of spatial memory in rats.Behavioural brain research · 2019Article
- Mammillothalamic Disconnection Alters Hippocampocortical Oscillatory Activity and Microstructure: Implications for Diencephalic Amnesia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Considering the Evidence for Anterior and Laterodorsal Thalamic Nuclei as Higher Order Relays to Cortex.Frontiers in molecular neuroscience · 2019Review
- Quantitative electroencephalographic changes and hippocampal atrophy in diabetic patients with mild cognitive impairment in Ismailia region.The Egyptian journal of neurology, psychiatry and neurosurgery · 2018Article
- Why do lesions in the rodent anterior thalamic nuclei cause such severe spatial deficits?Neuroscience and biobehavioral reviews · 2015Review
- How do mammillary body inputs contribute to anterior thalamic function?Neuroscience and biobehavioral reviews · 2015Review
- Article
- Harnessing the power of theta: natural manipulations of cognitive performance during hippocampal theta-contingent eyeblink conditioning.Frontiers in systems neuroscience · 2015Review
- A model of synaptic plasticity: activation of mGluR I induced long-term theta oscillations in medial septal diagonal band of rat brain slice.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2014Article
- Segregation of parallel inputs to the anteromedial and anteroventral thalamic nuclei of the rat.The Journal of comparative neurology · 2013Article
- The anterior thalamus is critical for overcoming interference in a context-dependent odor discrimination task.Behavioral neuroscience · 2012Article
- Specific EEG changes associated with atrophy of hippocampus in subjects with mild cognitive impairment and Alzheimer's disease.International journal of Alzheimer's disease · 2012Article
- Default-mode-like network activation in awake rodents.PloS one · 2011Article
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Authors and funding
6 authors.
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Abstract
Hippocampally-driven oscillatory activity at theta frequency is found in the diencephalon, but an understanding of the fundamental role of theta in the hippocampo-diencephalic circuit remains elusive. An important strategy in determining how activity modifies oscillatory properties of hippocampo-diencephalic circuitry comprises investigations of anterior thalamic responses to their main inputs: the descending dorsal fornix and the ascending mammillothalamic tract. Here, we show that the amplitude of thalamic theta spectral power selectively increases after plasticity-inducing stimulation of the dorsal fornix, but not of the mammillothalamic tract in urethane-anaesthetized young male rats. Furthermore, we show that low-frequency stimulation (LFS) significantly augments the fornix-driven theta ratio (theta over delta power, T-ratio), in parallel with depressing thalamic synaptic responses. However, the mammillothalamic synaptic response after LFS did not correlate with the slow band of theta oscillation (low T-ratio), but did correlate positively with the fast band of theta oscillation (high T-ratio). Our data demonstrate that the descending direct fornix projection is a pathway that modulates theta rhythm in the hippocampo-diencephalic circuit, resulting in dynamic augmentation of thalamic neuronal responsiveness. These findings suggest that hippocampal theta differentially affects synaptic integration in the different structures with which the hippocampus is reciprocally connected.
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