Evidence map›Paper›PMID 21458737›Full record

ArticlePaediatric respiratory reviews2011

Diagnosing and preventing chronic suppurative lung disease (CSLD) and bronchiectasis.

A B Chang, C A Byrnes, M L Everard

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Paediatric respiratory reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02258763 (Pneumonia in Children), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02258763 phase4completednot on this mapstarted 2014, after this paper: background citation

Pneumonia in Children: Aetiology, Ideal Antibiotic Duration, Quality of Life

TypeinterventionalSponsorUniversity of MalayaRan2014 to 2018Enrolled19ConditionsPneumoniaArmsAmoxicillin-Potassium Clavulanate Combination, Placebo
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 63 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Bronchiectasis in children in a high HIV and tuberculosis prevalence setting.African journal of thoracic and critical care medicine · 2024
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Chronic suppurative lung disease in adults.Journal of thoracic disease · 2016
    Article
  13. Article
  14. Review
  15. A review of the role ofPneumonia (Nathan Qld.) · 2015
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

A B ChangChild Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, NT; Queensland Children's Respiratory Centre and Queensland Children's Medical Research Institute, Royal Children's Hospital, Brisbane, Australia. annechang@ausdoctors.net
C A Byrnes
M L Everard
Charles Darwin University · AUSheffield Children's Hospital · GBUniversity of Auckland · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current diagnostic labelling of childhood bronchiectasis by radiology has substantial limitations. These include the requirement for two high resolution computerised tomography [HRCT] scans (with associated adversity of radiation) if criteria is adhered to, adoption of radiological criteria for children from adult data, relatively high occurrence of false negative, and to a smaller extent false positive, in conventional HRCT scans when compared to multi-detector CT scans, determination of irreversible airway dilatation, and absence of normative data on broncho-arterial ratio in children. A paradigm presenting a spectrum related to airway bacteria, with associated degradation and inflammation products causing airway damage if untreated, entails protracted bacterial bronchitis (at the mild end) to irreversible airway dilatation with cystic formation as determined by HRCT (at the severe end of the spectrum). Increasing evidence suggests that progression of airway damage can be limited by intensive treatment, even in those predestined to have bronchiectasis (eg immune deficiency). Treatment is aimed at achieving a cure in those at the milder end of the spectrum to limiting further deterioration in those with severe 'irreversible' radiological bronchiectasis.

Indexed as

AsthmaBronchiectasisBronchitisChronic DiseaseDiagnosis, DifferentialHumansSuppurationTomography, X-Ray Computed

Identifiers

PMID21458737
PMCPMC7173082
OpenAlexW2064953183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.