Evidence map›Paper›PMID 21458585›Full record

ReviewMicrobes and infection2011

The cell biology of cryptosporidium infection.

Steven P O'Hara, Xian-Ming Chen

Abstract readReview
In one paragraph

Review in Microbes and infection, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 112 citations in OpenAlex.

  1. Deciphering Host-Pathogen Interactions: Role ofPathogens (Basel, Switzerland) · 2025
    Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Use of nanoparticles, a modern means of drug delivery, against cryptosporidiosis.Journal of advanced veterinary and animal research · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Detection ofMicroorganisms · 2022
    Review
  13. Public health and ecological significance of rodents inOne health (Amsterdam, Netherlands) · 2022
    Review
  14. Protein Kinase C-α Is a Gatekeeper ofInfection and immunity · 2022
    Article
  15. PersistentMicroorganisms · 2021
    Article
  16. Review
  17. Review
  18. Microorganisms · 2020
    Review
  19. Article
  20. Vitamin and cofactor acquisition in apicomplexans: SynthesisThe Journal of biological chemistry · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Steven P O'HaraCenter for Basic Research in Digestive Diseases, Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA. ohara.steven@mayo.edu
Xian-Ming Chen
CHI Health Creighton University Medical Center - Bergan Mercy · USMayo Clinic · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI GREGORY J. GORES · 2009 to 2026
$22.2M
Pathophysiology of cholangiocyte responses to microbial pathogensR01AI089713 · NIAID · MAYO CLINIC ROCHESTER · PI O'HARA, STEVEN P · 2011 to 2015
$1.8M
NIAID NIH HHS R01 AI089713NIDDK NIH HHS P30 DK084567
6 · The paper itself

Abstract

Cryptosporidiosis remains a significant cause of enteric disease worldwide. Basic investigations of host: pathogen interactions have revealed the intricate processes mediating infection. The following summarizes the interactions that mediate infection and the host responses that both permit and ultimately clear the infection.

Indexed as

CryptosporidiosisCryptosporidiumHost-Parasite InteractionsHumans

Identifiers

PMID21458585
PMCPMC3130844
OpenAlexW2050213669

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.