Evidence map›Paper›PMID 21458441›Full record

ArticleDevelopmental biology2011

The FaceBase Consortium: a comprehensive program to facilitate craniofacial research.

Harry Hochheiser, Bruce J Aronow, Kristin Artinger, Terri H Beaty, James F Brinkley, Yang Chai, David Clouthier, Michael L Cunningham, Michael Dixon, Leah Rae Donahue and 15 more

Abstract read
In one paragraph

Article in Developmental biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 2 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. 3D stereophotogrammetry versus traditional craniofacial anthropometry: Comparing measurements from the 3D facial norms database to Farkas's North American norms.American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics · 2019
    Article
  13. Article
  14. Soft tissue nasal asymmetry as an indicator of orofacial cleft predisposition.American journal of medical genetics. Part A · 2018
    Article
  15. Article
  16. Facial Genetics: A Brief Overview.Frontiers in genetics · 2018
    Review
  17. Review
  18. Hypertelorism and Orofacial Clefting Revisited: An Anthropometric Investigation.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2017
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 18 institutions in 3 countries.

Harry HochheiserDepartment of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15232, USA.
Bruce J Aronow
Kristin Artinger
Terri H Beaty
James F Brinkley
Yang Chai
David Clouthier
Michael L Cunningham
Michael Dixon
Leah Rae Donahue
Scott E Fraser
Benedikt Hallgrimsson
Junichi Iwata
Ophir Klein
Mary L Marazita
Jeffrey C Murray
Stephen Murray
Fernando Pardo-Manuel de Villena
John Postlethwait
Steven Potter
Linda Shapiro
Richard Spritz
Axel Visel
Seth M Weinberg
Paul A Trainor
University of Pittsburgh · USJackson Laboratory · USUniversity of Colorado Anschutz Medical Campus · USUniversity of Southern California · USUniversity of Washington · USCalifornia Institute of Technology · USCincinnati Children's Hospital Medical Center · USJohns Hopkins University · USNorth Iowa Area Community College · USSeattle Children's Hospital · USStowers Institute for Medical Research · USUnited States Department of Energy · USUniversity of Calgary · CAUniversity of California, San Francisco · USUniversity of Cincinnati · USUniversity of Colorado Denver · USUniversity of Iowa · USUniversity of Manchester · GB

Funding

FaceBase Management and Coordination HubU01DE020057 · NIDCR · UNIVERSITY OF IOWA · PI MARAZITA, MARY L., MURRAY, JEFFREY C · 2009 to 2014
$8.9M
Intrinsic and extrinsic regulation of cranial mesodermR01DE016082 · NIDCR · STOWERS INSTITUTE FOR MEDICAL RESEARCH · PI TRAINOR, PAUL · 2004 to 2014
$3.9M
Technology Project: Shape-Based Retrieval of 3D Craniofacial DataU01DE020050 · NIDCR · UNIVERSITY OF WASHINGTON · PI SHAPIRO, LINDA · 2009 to 2013
$3.8M
Technology Project: Genetic Tools and Resources for Orofacial Clefting ResearchU01DE020052 · NIDCR · JACKSON LABORATORY · PI MURRAY, STEPHEN A · 2009 to 2013
$3.2M
Functional analysis of neural crest & palate: Imaging craniofacial developmentU01DE020063 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FRASER, SCOTT E · 2009 to 2013
$2.9M
Genetic Determinants of Orofacial Shape and Relationship to Cleft Lip/PalateU01DE020054 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI SPRITZ, RICHARD ANDREW · 2009 to 2014
$2.4M
Research Project: Genome-Wide Atlas of Craniofacial Transcriptional EnhancersU01DE020060 · NIDCR · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI VISEL, AXEL · 2009 to 2013
$2.1M
RESEARCH ON FUNCTIONAL GENOMICS, IMAGE ANALYSIS AND RESCUE OF CLEFT PALATEU01DE020065 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHAI, YANG · 2009 to 2013
$2.1M
3D Analysis of Normal Facial Variation: Data Repository and Genetics (Research)U01DE020078 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARAZITA, MARY L., WEINBERG, SETH M · 2009 to 2013
$2.0M
Idenfication of miRNAs involved midfacial development and cleftingU01DE020076 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI ARTINGER, KRISTIN, CLOUTHIER, DAVID E. · 2009 to 2013
$1.9M
Global Gene Expression Atlas of Craniofacial Development (Research Project)U01DE020049 · NIDCR · CINCINNATI CHILDRENS HOSP MED CTR · PI POTTER, S. STEVEN · 2009 to 2013
$1.4M
Oral Clefts: Moving from Genome Wide Studies Toward Functional GenomicsU01DE020073 · NIDCR · JOHNS HOPKINS UNIVERSITY · PI BEATY, TERRI H · 2009 to 2013
$1.1M
NIDCR NIH HHS R01 DE016082NIDCR NIH HHS U01 DE020049NIDCR NIH HHS U01 DE020050NIDCR NIH HHS U01 DE020052NIDCR NIH HHS U01 DE020054NIDCR NIH HHS U01 DE020057NIDCR NIH HHS U01-DE020057NIDCR NIH HHS U01 DE020060NIDCR NIH HHS U01 DE020063NIDCR NIH HHS U01 DE020065NIDCR NIH HHS U01 DE020073NIDCR NIH HHS U01 DE020076NIDCR NIH HHS U01 DE020078NIDCR NIH HHS U01-DE20049NIDCR NIH HHS U01-DE20050NIDCR NIH HHS U01-DE20052NIDCR NIH HHS U01-DE20054NIDCR NIH HHS U01-DE20060NIDCR NIH HHS U01-DE20063NIDCR NIH HHS U01-DE20065NIDCR NIH HHS U01-DE20073NIDCR NIH HHS U01-DE20076NIDCR NIH HHS U01-DE20078
6 · The paper itself

Abstract

The FaceBase Consortium consists of ten interlinked research and technology projects whose goal is to generate craniofacial research data and technology for use by the research community through a central data management and integrated bioinformatics hub. Funded by the National Institute of Dental and Craniofacial Research (NIDCR) and currently focused on studying the development of the middle region of the face, the Consortium will produce comprehensive datasets of global gene expression patterns, regulatory elements and sequencing; will generate anatomical and molecular atlases; will provide human normative facial data and other phenotypes; conduct follow up studies of a completed genome-wide association study; generate independent data on the genetics of craniofacial development, build repositories of animal models and of human samples and data for community access and analysis; and will develop software tools and animal models for analyzing and functionally testing and integrating these data. The FaceBase website (http://www.facebase.org) will serve as a web home for these efforts, providing interactive tools for exploring these datasets, together with discussion forums and other services to support and foster collaboration within the craniofacial research community.

Indexed as

Databases, FactualGene Expression ProfilingResearchComputational BiologyFaceHumansSkullSoftware

Identifiers

PMID21458441
PMCPMC3440302
OpenAlexW2089599444

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.