Evidence map›Paper›PMID 21457576›Full record

Trial reportBMC musculoskeletal disorders2011

Low bone mineral density is a significant risk factor for low-energy distal radius fractures in middle-aged and elderly men: a case-control study.

Jannike Øyen, Gudrun Rohde, Marc Hochberg, Villy Johnsen, Glenn Haugeberg

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC musculoskeletal disorders, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 32 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Observational
  5. Bone Microarchitecture and Distal Radius Fracture Pattern Complexity.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2019
    Article
  6. Article
  7. Does regional loss of bone density explain low trauma distal forearm fractures in men (the Mr F study)?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
  8. Article
  9. Article
  10. Calcium phosphate cement augmentation after volar locking plating of distal radius fracture significantly increases stability.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2014
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Clinical management of osteoporotic vertebral fracture treated with percutaneous vertebroplasty.Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Jannike ØyenDepartment of Public Health and Primary Health Care, University of Bergen, Bergen, Norway.
Gudrun Rohde
Marc Hochberg
Villy Johnsen
Glenn Haugeberg
Sørlandet Sykehus · NONorwegian University of Science and Technology · NOUniversity of Bergen · NOUniversity of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn general there is a lack of data on osteoporosis and fracture in men; this also includes low-energy distal radius fractures. The objectives of this study were to examine BMD and identify factors associated with distal radius fractures in male patients compared with controls recruited from the background population.

methodsIn a 2-year period, 44 men 50 years or older were diagnosed with low-energy distal radius fractures, all recruited from one hospital. The 31 men who attended for osteoporosis assessment were age-matched with 35 controls. Demographic and clinical data were collected and BMD at femoral neck, total hip and spine L2-4 was assessed by dual energy X-ray absorptiometry.

resultsApart from weight and living alone, no significant differences were found between patient and controls for demographic variables (e.g. height, smoking) and clinical variables (e.g. co-morbidity, use of glucocorticoids, osteoporosis treatment, falls and previous history of fracture). However, BMD expressed as T-score was significant lower in patients than in controls at all measurement sites (femoral neck: -2.24 vs. -1.15, p < 0.001; Total hip: -1.65 vs. -0.64, p < 0.001; Spine L2-4: -1.26 vs. 0.25, p = 0.002). Among the potential risk factors for fracture evaluated, only reduced BMD was found to be significantly associated with increased risk for low-energy distal radius fractures in men.

conclusionThe results from our study indicate that reduced BMD is an important risk factor for low-energy distal radius fracture in men. This suggests that improvement of BMD by both pharmacological and non-pharmacological initiatives may be a strategy to reduce fracture risk in men.

Indexed as

Absorptiometry, PhotonAgedBone DensityCase-Control StudiesComorbidityHumansMaleMiddle AgedOsteoporosisProspective StudiesRadius FracturesRisk Factors

Identifiers

PMID21457576
PMCPMC3080838
OpenAlexW2023508626

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.