Evidence map›Paper›PMID 21457493›Full record

ReviewGenome biology2011

High-throughput phenotyping of multicellular organisms: finding the link between genotype and phenotype.

Rosangela Sozzani, Philip N Benfey

Abstract readReview
In one paragraph

Review in Genome biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. A Compact Imaging Platform for ConductingLife (Basel, Switzerland) · 2023
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Applications of comparative evolution to human disease genetics.Current opinion in genetics & development · 2015
    Review
  7. Single-cell phenomics in budding yeast.Molecular biology of the cell · 2015
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. 3D phenotyping and quantitative trait locus mapping identify core regions of the rice genome controlling root architecture.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Whole-animal imaging, gene function, and the Zebrafish Phenome Project.Current opinion in genetics & development · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rosangela SozzaniDepartment of Biology and IGSP Center for Systems Biology, Duke University, Durham, North Carolina, USA.
Philip N Benfey

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High-throughput phenotyping approaches (phenomics) are being combined with genome-wide genetic screens to identify alterations in phenotype that result from gene inactivation. Here we highlight promising technologies for 'phenome-scale' analyses in multicellular organisms.

Indexed as

PhenotypeAnimalsAutomation, LaboratoryBiotechnologyCaenorhabditis elegansGenetic Association StudiesHigh-Throughput Screening AssaysMicePlantsRNA Interference

Identifiers

PMID21457493
PMCPMC3129668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.