Evidence map›Paper›PMID 21457103›Full record

ArticleAntioxidants & redox signaling2011

Redox going with vascular shear stress.

Noriko Noguchi, Hanjoong Jo

Abstract readEditorial
In one paragraph

Article in Antioxidants & redox signaling, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Fluid Mechanics, Arterial Disease, and Gene Expression.Annual review of fluid mechanics · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 3 countries.

Noriko Noguchi
Hanjoong Jo
Doshisha University · JPEmory University · US

Funding

Biology, Biomechanics and AtherosclerosisR01HL070531 · NHLBI · EMORY UNIVERSITY · PI TAYLOR, WILLIAM ROBERT · 2002 to 2012
$12.7M
Shear and Oxidative Stress Regulate Endothelial Matrix MetalloproteinaseP01HL075209 · NHLBI · EMORY UNIVERSITY · PI GRIENDLING, KATHY K · 2004 to 2008
$7.5M
Shear Stress, BMP and Aortic Valve InflammationR01HL087012 · NHLBI · EMORY UNIVERSITY · PI JO, HANJOONG · 2007 to 2010
$1.9M
NHLBI NIH HHS HL75209NHLBI NIH HHS HL87012NHLBI NIH HHS R01 HL070531
6 · The paper itself

Abstract

Shear stress plays a critical role in the regulation of vascular biology and diseases, such as atherosclerosis, via modulation of signal transduction and redox balance. Atherosclerosis preferentially occurs in a site-specific manner linked to disturbed flow. In this Forum on Vascular Shear Stress, emerging role of redox-dependent molecular mechanisms by which shear stress regulates pro- and antiatherogenic responses in endothelial cells both in vitro and in vivo are reviewed in depth by experts. This Forum also provides comprehensive reviews regarding experimental apparatus and in vivo, ex vivo, and in vitro systems used for shear stress studies.

Indexed as

Stress, MechanicalAnimalsAtherosclerosisEndothelial CellsHemodynamicsHumansOxidation-ReductionShear Strength

Identifiers

PMID21457103
PMCPMC3144424
OpenAlexW1967966076

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.