Evidence map›Paper›PMID 21456512›Full record

ReviewChemical reviews2011

Genetically encodable fluorescent biosensors for tracking signaling dynamics in living cells.

Robert H Newman, Matthew D Fosbrink, Jin Zhang

Abstract readReview
In one paragraph

Review in Chemical reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed.

  1. Article
  2. A Constellation of Fluorescent Biosensors to Illuminate the Galaxy of Protein Kinases.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Mining Genetically Encoded Biosensors from Filamentous Fungi.Journal of fungi (Basel, Switzerland) · 2026
    Review
  4. Review
  5. Protein Engineering for Spatiotemporally Resolved Cellular Monitoring.Annual review of analytical chemistry (Palo Alto, Calif.) · 2025
    Review
  6. Article
  7. Experimental Approaches to Visualize Effector Protein Translocation During Host-Pathogen Interactions.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  8. Review
  9. Article
  10. Multipartite Fluorogenic Sensors for Monitoring Tyrosine Phosphatase Activity.Chembiochem : a European journal of chemical biology · 2024
    Article
  11. Article
  12. Imaging the Raf-MEK-ERK Signaling Cascade in Living Cells.International journal of molecular sciences · 2024
    Article
  13. Article
  14. OptimizingFrontiers in microbiology · 2024
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert H NewmanDepartment of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Matthew D Fosbrink
Jin Zhang

Funding

JHU-UMD Diabetes Research CenterP30DK079637 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI WONDISFORD, FREDRIC E. · 2013 to 2017
$9.7M
Mechanisms of Compartmentalized cAMP SignalingR01DK073368 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jin Zhang · 2006 to 2026
$7.6M
Creating a Genetically Encodable Nano-Compass to Navigate in Molecular NetworksDP1OD006419 · OD · JOHNS HOPKINS UNIVERSITY · PI ZHANG, JIN · 2009 to 2011
$2.5M
NIDDK NIH HHS DK073368NIDDK NIH HHS P30 DK079637NIDDK NIH HHS R01 DK073368NIH HHS DP1 OD006419NIH HHS DP1OD006419
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biosensing TechniquesGreen Fluorescent ProteinsSignal TransductionGreen Fluorescent Proteins

Identifiers

PMID21456512
PMCPMC3092831

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.