ArticleIndian journal of pharmacology2011
Monitoring of incidence, severity, and causality of adverse drug reactions in hospitalized patients with cardiovascular disease.
Article in Indian journal of pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Mortality among patients due to adverse drug reactions that occur following hospitalisation: a meta-analysis.European journal of clinical pharmacology · 2019Pooled it
- Implementation of the pharmacovigilance database in the usage of antibiotics in a tertiary care hospital: A pilot study.Health science reports · 2024Article
- Prevalence and factors associated with adverse drug reactions among heart failure patients hospitalized at Mbarara Regional Referral Hospital, Uganda.BMC cardiovascular disorders · 2022Observational
- Study of pattern & distribution of adverse drug reactions in acute coronary syndrome patients in a tertiary care hospital.The Indian journal of medical research · 2022Article
- Risk factors for adverse drug reactions associated with clopidogrel therapy.Open medicine (Warsaw, Poland) · 2022Article
- Pharmacovigilance in India: Present Scenario and Future Challenges.Drug safety · 2019Article
- Causality and preventability assessment of adverse drug events of antibiotics among inpatients having different lengths of hospital stay: a multicenter, cross-sectional study in Lahore, Pakistan.BMC pharmacology & toxicology · 2018Observational
- Article
- Study of adverse drug reactions in patients with diabetes attending a tertiary care hospital in New Delhi, India.The Indian journal of medical research · 2017Article
- Pattern of Adverse Drug Reactions Reported with Cardiovascular Drugs in a Tertiary Care Teaching Hospital.Journal of clinical and diagnostic research : JCDR · 2015Article
- Evaluation of potential drug - drug interactions in general medicine ward of teaching hospital in southern India.Journal of clinical and diagnostic research : JCDR · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients admitted to cardiology department are mostly on polypharmacy. So drug-drug interactions and adverse effects of drugs are quite common. Yet, there is a paucity of data regarding adverse drug reaction (ADR) monitoring in cardiology department in India. The present study is an effort to fill up these lacunae. MATERIALS AND
methodsA prospective, observational study registering 966 indoor cardiology patients according to predetermined inclusion and exclusion criteria was conducted for one year. ADR profile was noted by spontaneous reporting and intensive monitoring. Naranjo ADR probability scale was used to establish the causality.
resultsA total of 208 ADRs were reported from 188 patients (19.5%). Of these 188 patients, 62 patients (33%) were hospitalized primarily due to the development of ADRs, while 126 (67%) patients developed ADRs during hospital stay. Nitrates were the most common offender drug group (17.8%).
conclusionDevelopment of ADR in one of every five cardiac patient points toward a grave situation, but a higher incidence of Type A reactions in cardiology department means that these can be avoided.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.