Sodium iodide symporter SPECT imaging of a patient treated with oncolytic adenovirus Ad5/3-Δ24-hNIS.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Oncolytic Viruses in the Era of Omics, Computational Technologies, and Modeling: Thesis, Antithesis, and Synthesis.International journal of molecular sciences · 2023
   Review
2. Toward comprehensive imaging of oncolytic viroimmunotherapy.Molecular therapy oncolytics · 2021
   Review
3. Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion.Molecular therapy oncolytics · 2021
   Article
4. Oncolytic viruses for cancer immunotherapy.Journal of hematology & oncology · 2020
   Review
5. Positive radionuclide imaging of miRNA expression using RILES and the human sodium iodide symporter as reporter gene is feasible and supports a protective role of miRNA-23a in response to muscular atrophy.PloS one · 2017
   Article
6. The use of the NIS reporter gene for optimizing oncolytic virotherapy.Expert opinion on biological therapy · 2016
   Review
7. Oncolytic immunotherapy: where are we clinically?Scientifica · 2014
   Review
8. HSV-NIS, an oncolytic herpes simplex virus type 1 encoding human sodium iodide symporter for preclinical prostate cancer radiovirotherapy.Cancer gene therapy · 2013
   Article
9. A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2012
   Article
10. SPECT/CT imaging of hNIS-expression after intravenous delivery of an oncolytic adenovirus and 131I.PloS one · 2012
    Article
11. Theranostic potential of oncolytic vaccinia virus.Theranostics · 2012
    Article
12. Normalisation to blood activity is required for the accurate quantification of Na/I symporter ectopic expression by SPECT/CT in individual subjects.PloS one · 2012
    Article

Corrections and comments

• Comment on
  Phase I study of noninvasive imaging of adenovirus-mediated gene expression in the human prostate.2008

Authors and funding

13 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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