ArticleMedical science monitor : international medical journal of experimental and clinical research2011
Effect of hormone replacement therapy (HRT) on periodontal status of postmenopausal women.
Article in Medical science monitor : international medical journal of experimental and clinical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- Periodontal Status and Oral Health-Related Quality of Life among Postmenopausal Women Visiting Tertiary Government Hospital.Journal of menopausal medicine · 2026Article
- Oral Health Across the Menopausal Transition: Biological Pathways, Clinical Implications, and Future Perspectives.Journal of clinical medicine · 2026Review
- Article
- Unraveling the Relationship Between Osteoporosis, Treatment Modalities, and Oral Health: A Comprehensive Review.Cureus · 2023Review
- Association of periodontitis with menopause and hormone replacement therapy: a hospital cohort study using a common data model.Journal of periodontal & implant science · 2023Article
- Hormonal Fluctuations and Periodontal Status in Postmenopausal Women.International journal of dentistry · 2022Article
- Article
- A Comparative Analysis of Pre- and Postmenopausal Females with Periodontitis and Its Response to a Non Invasive Clinical Approach.Journal of menopausal medicine · 2017Article
- Periodontal treatment outcomes in post menopausal women receiving hormone replacement therapy.Journal of Istanbul University Faculty of Dentistry · 2015Article
- Serum γ-glutamyltransferase level is associated with periodontal disease independent of drinking habits in Japanese adults.Medical science monitor : international medical journal of experimental and clinical research · 2014Article
- Osteoporosis/osteopenia as an independent factor associated with periodontitis in postmenopausal women: a case-control study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2013Article
- Potential implications of adjuvant endocrine therapy for the oral health of postmenopausal women with breast cancer.Breast cancer research and treatment · 2013Review
- Effects of systemic ornidazole, systemic and local compound ornidazole and pefloxacin mesylate on experimental periodontitis in rats.Medical science monitor : international medical journal of experimental and clinical research · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risks/benefits balance of hormone replacement therapy (HRT) is controversial. The aim of this study was to assess the periodontal status of a postmenopausal women group receiving HRT and to determine the effects of HRT on clinical measures of periodontal disease. MATERIAL/
methodsNinety-one postmenopausal women, 52 taking HRT (HRT+) and 39 not taking HRT (HRT-), completed the study. Clinical parameters measured included visible supragingival plaque, probing pocket depth (PD) and clinical attachment level (CAL). Gingival status was recorded as gingival bleeding on probing (BOP). Previous oral contraceptive use and current and past smoking status were also assessed.
resultsData indicated that PD and CAL were not significantly different between HRT+ patients and HRT- patients (P=0.8067 and P=0.1627, respectively). The HRT+ group exhibited significantly lower visible plaque levels compared to the control group (P<0.0001). The percentage of gingival sites with positive BOP was significantly lower in the HRT+ group compared to the HRT- group (34.85% vs. 65.15%; P=0.0007). Plaque accumulation was also tested in ANCOVA as a possible explanatory variable for the differences observed in gingival bleeding. The ANCOVA showed no significant differences in gingival bleeding between HRT+ and HRT- women (P=0.4677). No significant differences in past smoking status and oral contraceptive use were detected between HRT+ and HRT- women (P=0.9999 and P=0.0845, respectively).
conclusionsThese findings indicated that long-term HRT was not associated with relevant effects on periodontal status and clinical measures of periodontal disease, thus suggesting that HRT may not confer protection against periodontitis in postmenopausal women.
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