ArticleVirology journal2011
Clinical characteristics and risk factors of sporadic Hepatitis E in central China.
Article in Virology journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Prevalence of hepatitis E virus in China from 1997 to 2022: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Risk factors analysis for progression to severe hepatitis in acute hepatitis E: a retrospective study of 146 hospitalized cases.BMC infectious diseases · 2025Article
- Article
- Clinical characteristics of 1279 patients with hepatitis E in Tianjin.Epidemiology and infection · 2023Article
- Clinical-biochemical profile and etiology of acute viral hepatitis in hospitalized young adults at tertiary care center.Journal of family medicine and primary care · 2020Article
- Prognostic Significance of End-Stage Liver Diseases, Respiratory Tract Infection, and Chronic Kidney Diseases in Symptomatic Acute Hepatitis E.Frontiers in cellular and infection microbiology · 2020Article
- Superinfective Hepatitis E Virus Infection Aggravates Hepatocytes Injury in Chronic Hepatitis B.Current medical science · 2019Article
- The Bama miniature swine is susceptible to experimental HEV infection.Scientific reports · 2016Article
- Surveillance of hepatitis E virus contamination in shellfish in China.International journal of environmental research and public health · 2015Article
- Genetic host specificity of hepatitis E virus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Article
- A study of viral hepatitis e infection in a tertiary care hospital in mysore, South India.Open forum infectious diseases · 2014Article
- Epidemiology of hepatitis E virus in China: results from the Third National Viral Hepatitis Prevalence Survey, 2005-2006.PloS one · 2014Article
- Seasonal pattern of hepatitis E virus prevalence in swine in two different geographical areas of China.Epidemiology and infection · 2013Article
- Variable Outcome of Acute Viral Hepatitis in Diabetic and Nondiabetic Patients in Bangladesh.Euroasian journal of hepato-gastroenterologyArticle
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEpidemiological investigations, detections and vaccines of hepatitis E (HE) have been paid a focus of attention in prior studies, while studies on clinical features and risk factors with a large number of sporadic HE patients are scarce.
resultsSporadic HE can occur throughout the year, with the highest incidence rate in the first quarter of a year, in central of China. Of the 210 patients, 85.2% were male, and the most common clinical symptoms were jaundice (85.7%), fatigue (70.5%) and anorexia (64.8%). Total bilirubin (TBil), blood urea nitrogen (BUN), and international normalized ratio (INR) were found as major risk factors for death of HE patients. There was an overall mortality of 10%, and the mortality in the cirrhotic and non-cirrhotic group was 25% and 6.47%, respectively. Moreover, hepatitis E virus (HEV) infected patients with liver cirrhosis had a higher mortality and incidence of complications.
conclusionsTBil, BUN, and INR are major risk factors of mortality for HE. Liver cirrhosis can aggravate HE, and lead to a higher mortality. HEV infection can cause decompensation in patients with cirrhosis, as evidenced by a worsening Child-Pugh score.
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