Evidence map›Paper›PMID 21453435›Full record

ReviewMolecular plant pathology2011

The coat protein leads the way: an update on basic and applied studies with the Brome mosaic virus coat protein.

C Cheng Kao, Peng Ni, Masarapu Hema, Xinlei Huang, Bogdan Dragnea

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular plant pathology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Article
  3. Laboratory evolution of virus-like nucleocapsids from nonviral protein cages.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Mechanisms of virus assembly.Annual review of physical chemistry · 2015
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

C Cheng KaoDepartment of Molecular and Cellular Biochemistry, Indiana University, Bloomington, IN 47405, USA. ckao@indiana.edu
Peng Ni
Masarapu Hema
Xinlei Huang
Bogdan Dragnea
Indiana University Bloomington · USSri Venkateswara University · IN

Funding

Molecular biology of viral capsidsR01AI090280 · NIAID · TRUSTEES OF INDIANA UNIVERSITY · PI KAO, CHENG C · 2010 to 2013
$1.3M
Molecular Basis for Biological Membrane OrganizationR13GM081929 · NIGMS · KEYSTONE SYMPOSIA · PI ROBERTSON, ANDREW D · 2008 to 2008
$5k
NIAID NIH HHS 1R01AI090280NIAID NIH HHS R01 AI090280NIGMS NIH HHS GM081929NIGMS NIH HHS R13 GM081929
6 · The paper itself

Abstract

The Brome mosaic virus (BMV) coat protein (CP) accompanies the three BMV genomic RNAs and the subgenomic RNA into and out of cells in an infection cycle. In addition to serving as a protective shell for all of the BMV RNAs, CP plays regulatory roles during the infection process that are mediated through specific binding of RNA elements in the BMV genome. One regulatory RNA element is the B box present in the 5' untranslated region (UTR) of BMV RNA1 and RNA2 that play important roles in the formation of the BMV replication factory, as well as the regulation of translation. A second element is within the tRNA-like 3' UTR of all BMV RNAs that is required for efficient RNA replication. The BMV CP can also encapsidate ligand-coated metal nanoparticles to form virus-like particles (VLPs). This update summarizes the interaction between the BMV CP and RNAs that can regulate RNA synthesis, translation and RNA encapsidation, as well as the formation of VLPs.

Indexed as

BromovirusCapsid ProteinsGene Expression Regulation, ViralProtein Structure, SecondaryRNA, ViralCapsid Proteinscoat protein, Brome mosaic virusRNA, Viral

Identifiers

PMID21453435
PMCPMC6640235
OpenAlexW2116063232

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.