ReviewNanotechnology2011
Nanoscale tissue engineering: spatial control over cell-materials interactions.
Review in Nanotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Construction, evaluation, and applications of renal barrier-on-a-chip system.Bioactive materials · 2026Review
- Extracellular-Matrix-Mimetic Hydrogels by Using Nanomaterials.International journal of molecular sciences · 2025Review
- DNA origami: Interrogating the nano-landscape of immune receptor activation.Biophysical journal · 2024Review
- Nanocomposite Hydrogels as Functional Extracellular Matrices.Gels (Basel, Switzerland) · 2023Review
- Encoding microcarriers for biomedicine.Smart medicine · 2023Review
- Tuning three-dimensional nano-assembly in the mesoscale via bis(imino)pyridine molecular functionalization.Scientific reports · 2022Article
- Cell-Instructive Surface Gradients of Photoresponsive Amyloid-like Fibrils.ACS biomaterials science & engineering · 2021Article
- Reversible control of biomaterial properties for dynamically tuning cell behavior.Journal of applied polymer science · 2020Article
- Recapitulating complex biological signaling environments using a multiplexed, DNA-patterning approach.Science advances · 2020Article
- Functionalization of Electrospun Nanofibers and Fiber Alignment Enhance Neural Stem Cell Proliferation and Neuronal Differentiation.Frontiers in bioengineering and biotechnology · 2020Article
- Self-assemble peptide biomaterials and their biomedical applications.Bioactive materials · 2019Review
- Surface Hydrophilicity of Poly(l-Lactide) Acid Polymer Film Changes the Human Adult Adipose Stem Cell Architecture.Polymers · 2018Article
- Surface nanocavitation of titanium modulates macrophage activity.International journal of nanomedicine · 2018Article
- Vascular Cell Co-Culture on Silk Fibroin Matrix.Polymers · 2018Article
- Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering.Gels (Basel, Switzerland) · 2016Review
- Extracellular matrix elasticity and topography: material-based cues that affect cell function via conserved mechanisms.Journal of biomedical materials research. Part A · 2015Review
- Recent advances in bioprinting and applications for biosensing.Biosensors · 2014Review
- Biological effects of Spirulina (Arthrospira) biopolymers and biomass in the development of nanostructured scaffolds.BioMed research international · 2014Review
- Recent advances in application of biosensors in tissue engineering.BioMed research international · 2014Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cells interact with the surrounding environment by making tens to hundreds of thousands of nanoscale interactions with extracellular signals and features. The goal of nanoscale tissue engineering is to harness these interactions through nanoscale biomaterials engineering in order to study and direct cellular behavior. Here, we review two- and three-dimensional (2- and 3D) nanoscale tissue engineering technologies, and provide a holistic overview of the field. Techniques that can control the average spacing and clustering of cell adhesion ligands are well established and have been highly successful in describing cell adhesion and migration in 2D. Extension of these engineering tools to 3D biomaterials has created many new hydrogel and nanofiber scaffold technologies that are being used to design in vitro experiments with more physiologically relevant conditions. Researchers are beginning to study complex cell functions in 3D. However, there is a need for biomaterials systems that provide fine control over the nanoscale presentation of bioactive ligands in 3D. Additionally, there is a need for 2- and 3D techniques that can control the nanoscale presentation of multiple bioactive ligands and that can control the temporal changes in the cellular microenvironment.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.