Trial reportArchives of disease in childhood2011
Feather bedding and childhood asthma associated with house dust mite sensitisation: a randomised controlled trial.
Trial report in Archives of disease in childhood, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Impact of non-drug therapies on asthma control: A systematic review of the literature.The European journal of general practice · 2019Pooled it
- House dust mite control measures for asthma.The Cochrane database of systematic reviews · 2008Pooled it
- Forgotten but not gone: Particulate matter as contaminations of mucosal systems.Biophysics reviews · 2021Review
- A meta-analysis of baseline characteristics in trials on mite allergen avoidance in asthmatics: room for improvement.Clinical and translational allergy · 2020Review
- Time-Based Measurement of Personal Mite Allergen Bioaerosol Exposure over 24 Hour Periods.PloS one · 2016Article
- Predicting and reducing risk of exacerbations in children with asthma in the primary care setting: current perspectives.Pragmatic and observational research · 2016Review
- Rhinoviruses significantly affect day-to-day respiratory symptoms of children with asthma.The Journal of allergy and clinical immunology · 2015Article
- Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine.Environmental health perspectives · 2015Review
- Environmental assessment and exposure control of dust mites: a practice parameter.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2013Article
- Article
- Time for new methods for avoidance of house dust mite and other allergens.Current allergy and asthma reports · 2012Article
- Article
- Association of house dust mite-specific IgE with asthma control, medications and household pets.Asia Pacific allergy · 2011Article
- Impact of environmental controls on childhood asthma.Current allergy and asthma reports · 2011Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionObservational studies report inverse associations between the use of feather upper bedding (pillow and/or quilt) and asthma symptoms but there is no randomised controlled trial (RCT) evidence assessing the role of feather upper bedding as a secondary prevention measure.
objectiveTo determine whether, among children not using feather upper bedding, a new feather pillow and feather quilt reduces asthma severity among house dust mite (HDM) sensitised children with asthma over a 1-year period compared with standard dust mite avoidance advice, and giving children a new mite-occlusive mattress cover.
designRCT.
settingThe Calvary Hospital in the Australian Capital Territory and the Children's Hospital at Westmead, Sydney, New South Wales. PATIENTS: 197 children with HDM sensitisation and moderate to severe asthma. Intervention New upper bedding duck feather pillow and quilt and a mite-occlusive mattress cover (feather) versus standard care and a mite-occlusive mattress cover (standard).
main outcome measuresThe proportion of children reporting four or more episodes of wheeze in the past year; an episode of speech-limiting wheeze; or one or more episodes of sleep disturbance caused by wheezing; and spirometry with challenge testing. Statistical analysis included multiple logistic and linear regression.
resultsNo differences between groups were found for primary end points--frequent wheeze (OR 1.51, 95% CI 0.83 to 2.76, p=0.17), speech-limiting wheeze (OR 0.70, 95% CI 0.32 to 1.48, p=0.35), sleep disturbed because of wheezing (OR 1.17, 95% CI 0.64 to 2.13, p=0.61) or for any secondary end points. Secondary analyses indicated the intervention reduced the risk of sleep being disturbed because of wheezing and severe wheeze to a greater extent for children who slept supine.
conclusionNo differences in respiratory symptoms or lung function were observed 1 year after children with moderate-severe asthma and HDM sensitisation were given a mite-occlusive mattress cover and then received either feather upper bedding (pillow and quilt) or standard bedding care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.