Evidence map›Paper›PMID 21449665›Full record

ArticlePharmacogenomics2011

Polymorphisms present in G-protein-coupled receptor kinases and their effect on β-blocker treatment.

Philip W Raake, Walter J Koch, Patrick Most

Open access · greenAbstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacogenomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Philip W Raake
Walter J Koch
Patrick Most
Heidelberg University · DEThomas Jefferson University · US

Funding

Regulation of Beta-Adrenergic Receptor Signaling by S-NitrosylationP01HL075443 · NHLBI · DUKE UNIVERSITY · PI STAMLER, JONATHAN S. · 2004 to 2019
$26.1M
Targeting GRK2 in the HeartR01HL061690 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI KOCH, WALTER J. · 1998 to 2022
$4.2M
Gene Transfer and Myocardial FunctionR01HL056205 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI KOCH, WALTER J. · 1998 to 2008
$2.6M
S100A1: A Novel Modulator of Myocardial Infarct Inflammation and RegenerationR01HL092130 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI PEPPEL, KARSTEN · 2008 to 2012
$2.2M
NHLBI NIH HHS P01 HL075443NHLBI NIH HHS R01 HL056205NHLBI NIH HHS R01 HL061690NHLBI NIH HHS R01 HL092130NHLBI NIH HHS R01 HL56205NHLBI NIH HHS R01 HL61690NHLBI NIH HHS R01 HL92130NHLBI NIH HHS R01 HL92130-02 S1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adrenergic beta-AntagonistsArrestinsDrug ResistanceG-Protein-Coupled Receptor Kinase 5G-Protein-Coupled Receptor KinasesHeart FailureHumansLeucinePolymorphism, GeneticReceptors, Adrenergic, betaSignal TransductionAdrenergic beta-AntagonistsArrestinsG-Protein-Coupled Receptor Kinase 5G-Protein-Coupled Receptor KinasesLeucineReceptors, Adrenergic, beta

Identifiers

PMID21449665
PMCPMC4104676
OpenAlexW2064923232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.