Evidence map›Paper›PMID 21448736›Full record

SynthesisDer Anaesthesist2011

[Estimation of substitution volume after burn trauma. Systematic review of published formulae].

O Spelten, W A Wetsch, S Braunecker, H Genzwürker, J Hinkelbein

Erratum issuedAbstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Der Anaesthesist, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

O SpeltenKlinik für Anästhesiologie und Operative Intensivmedizin, Universitätsklinikum Köln, Kerpener Strasse 62, Köln, Germany. oliver.spelten@uk-koeln.de
W A Wetsch
S Braunecker
H Genzwürker
J Hinkelbein
Poliklinik für Endokrinologie, Diabetologie und Präventivmedizin · DEUniversity Hospital Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFluid resuscitation after severe burns remains a challenging task particularly in the preclinical and early clinical phases. To facilitate volume substitution after burn trauma several formulae have been published and evaluated, nevertheless, the optimal formula has not yet been identified.

methodsA systematic PubMed search was performed to identify published formulae for fluid resuscitation after severe burns. The search terms "burn", "thermal", "treatment", "therapy" or "resuscitation", "fluid", "formula" and "adult", "pediatric" or "paediatric" were used in various combinations. Analysis was limited to the period from 01.01.1950 to 30.06.2010 and database entries in PubMed (http://www.pubmed.com). Additionally, references cited in the papers were analyzed and relevant publications were also included. Publications and formulae were assessed and classified by two independent investigators.

resultsWithin the specified time frame eight publications (five original contributions and three book chapters) were identified of which three formulae recommended colloid solutions, four recommended electrolyte solutions and one suggested hypertonic solutions within the first 24 h for fluid resuscitation. Only one formula specifically dealt with fluid resuscitation in infants.

conclusionThe identified formulae led to sometimes strikingly diverse calculations of resuscitation fluid volumes. Therefore their use should be monitored closely and clinical values included. Urine output is a well established individual parameter. Use of colloid and hypertonic solutions leads to a reduced total fluid volume but is still controversially discussed.

Indexed as

AlgorithmsAdultBurnsChildColloidsFluid TherapyHumansHypertonic SolutionsInfantOsmolar ConcentrationRehydration SolutionsResuscitationUrodynamicsColloidsHypertonic SolutionsRehydration Solutions

Identifiers

PMID21448736
OpenAlexW2010769885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.