Evidence map›Paper›PMID 21448619›Full record

ArticlePediatric cardiology2011

Connective tissue disease presenting with signs and symptoms of pulmonary hypertension in children.

Shinichi Takatsuki, Jennifer B Soep, Michelle Calderbank, David Dunbar Ivy

Abstract readCase Reports
In one paragraph

Article in Pediatric cardiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [A clinical analysis of 15 children with systemic lupus erythematosus accompanied by pulmonary hypertension].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shinichi TakatsukiDepartment of Pediatrics, The Children's Hospital, University of Colorado Denver School of Medicine, 3123 East 16th Avenue, B100, Aurora, CO 80045, USA. tekeshin0621@msn.com
Jennifer B Soep
Michelle Calderbank
David Dunbar Ivy

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
ZORVIRAX ORAL SUSPENSION FOR SEVERE CHILDHOOD HERPES VIRUS INFECTIONSM01RR000069 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 1985 to 2008
$22.1M
Colorado Clinical and Translational Science Institute (UL1)UL1TR000154 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2012 to 2013
$20.4M
NCATS NIH HHS UL1 TR000154NCRR NIH HHS M01 RR000069NCRR NIH HHS M01-RR00069NCRR NIH HHS UL1 RR025780
6 · The paper itself

Abstract

Our case series describes three children who were initially diagnosed as having severe pulmonary arterial hypertension (PAH) and subsequently found to be positive for specific autoantibodies suggestive of an underlying autoimmune process. The signs and symptoms of PAH are subtle and may be part of the initial presentation of childhood connective tissue disease (CTD). Evaluation for connective tissue disease in the newly diagnosed pulmonary hypertension (PH) patient is important because early diagnosis of PH as well as CTD is crucial in the successful management of these complex patients. Ongoing monitoring for CTD in patients with severe PAH is warranted.

Indexed as

AdolescentChildConnective Tissue DiseasesDiagnosis, DifferentialEchocardiography, DopplerFamilial Primary Pulmonary HypertensionFemaleFollow-Up StudiesHumansHypertension, PulmonaryMalePulmonary Wedge PressureTomography, X-Ray Computed

Identifiers

PMID21448619
PMCPMC3142789

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.