Evidence map›Paper›PMID 21448305›Full record

ArticleInternational journal of medical sciences2011

Antimicrobial susceptibilities of Brucella isolates from various clinical specimens.

Yasemin Bayram, Hanifi Korkoca, Cenk Aypak, Mehmet Parlak, Aytekin Cikman, Selcuk Kilic, Mustafa Berktas

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Veterinary medicine international · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Antimicrobial susceptibility ofIranian journal of microbiology · 2019
    Article
  7. Antimicrobial Resistance inMicrobiology spectrum · 2018
    Review
  8. Article
  9. Article
  10. Antimicrobial susceptibility ofAntimicrobial resistance and infection control · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Brucellosis in low-income and middle-income countries.Current opinion in infectious diseases · 2013
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Yasemin BayramDepartment of Microbiology, Van Education and Research Hospital, 65100 Van, Turkey.
Hanifi Korkoca
Cenk Aypak
Mehmet Parlak
Aytekin Cikman
Selcuk Kilic
Mustafa Berktas
Van Yüzüncü Yıl Üniversitesi · TRAnkara Spine Center · TREducation Training And Research · USMuş Alparslan University · TRSivas State Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBrucellosis is a worldwide zoonotic disease and still constitutes a major public health problem. In the study we claimed to identify Brucella species from clinical samples of patients with active brucellosis from Van region of Eastern Anatolia and to determine in vitro antimicrobial susceptibilities of these strains to commonly used anti-Brucella agents and a possible new alternative tigecycline. MATERIALS AND

methodsA total of 56 Brucella isolates were enrolled the study and the identification of the isolates were based on conventional methods. In vitro activities of antimicrobials were evaluated by the E test method.

resultsAll isolates were identified as B. melitensis. MIC(90) values of doxycycline, streptomycin, rifampin, trimethoprim-sulfamethoxazole and tigecycline were 0.064 mg/L, 1 mg/L, 2 mg/L, 0.125 mg/L and 0.094 mg/L, respectively. Tigecycline had low MIC(50) and MIC(90) values against all B. melitensis strains; the highest MIC observed was 0.25 μg/mL.

conclusionOur data suggest that tigecycline can be a therapeutic alternative option for the treatment of brucellosis.

Indexed as

Anti-Bacterial AgentsBrucellaBrucella melitensisBrucellosisDoxycyclineHumansMicrobial Sensitivity TestsMinocyclineRifampinStreptomycinTigecyclineTrimethoprim, Sulfamethoxazole Drug CombinationTurkeyAnti-Bacterial AgentsDoxycyclineMinocyclineRifampinStreptomycinTigecyclineTrimethoprim, Sulfamethoxazole Drug Combinationantimicrobial susceptibilityBrucellaE-testtigecycline

Identifiers

PMID21448305
PMCPMC3053491
OpenAlexW2171267102

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.