ArticleAmerican journal of epidemiology2011
Prostate cancer and ambient pesticide exposure in agriculturally intensive areas in California.
Article in American journal of epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 104 citations in OpenAlex.
- Time for Re-Evaluating the Human Carcinogenicity of Ethylenedithiocarbamate Fungicides? A Systematic Review.International journal of environmental research and public health · 2022Pooled it
- Farming, reported pesticide use, and prostate cancer.American journal of men's health · 2013Pooled it
- Prostate cancer and toxicity from critical use exemptions of methyl bromide: environmental protection helps protect against human health risks.Environmental health : a global access science source · 2012Pooled it
- Duration of agricultural pesticide exposure application and Parkinson's disease in California's central valley.Environmental research, health : ERH · 2026Article
- Exceptional use: examining methyl bromide applications in California 2016-2022.Environmental research communications · 2026Article
- Article
- Persistent organic pollutants and prostate cancer: multiple mechanisms and comprehensive control strategies.Frontiers in cell and developmental biology · 2026Review
- Prenatal pesticide exposure and neuroblastoma - A statewide case-control study in California.Environmental research · 2025Article
- Preconception and first trimester exposure to pesticides and associations with stillbirth.American journal of epidemiology · 2025Article
- Environmental Health Assessment by Local Environmental Justice Experts for Evidence-based Decision-making in an Agricultural Community of Northern California.Community science · 2024Article
- Lysosomal genes contribute to Parkinson's disease near agriculture with high intensity pesticide use.NPJ Parkinson's disease · 2024Article
- Agricultural paraquat dichloride use and Parkinson's disease in California's Central Valley.International journal of epidemiology · 2024Article
- A pesticide and iPSC dopaminergic neuron screen identifies and classifies Parkinson-relevant pesticides.Nature communications · 2023Article
- Proximity to residential and workplace pesticides application and the risk of progression of Parkinson's diseases in Central California.The Science of the total environment · 2023Article
- Development of a Qualitative Test to Detect the Presence of Organophosphate Pesticides on Fruits and Vegetables.Life (Basel, Switzerland) · 2023Article
- Contributions of nearby agricultural insecticide applications to indoor residential exposures.Environment international · 2023Article
- Prenatal ambient pesticide exposure and childhood retinoblastoma.International journal of hygiene and environmental health · 2022Article
- Area-Based Geocoding: An Approach to Exposure Assessment Incorporating Positional Uncertainty.GeoHealth · 2021Article
- Association between environmental quality and prostate cancer stage at diagnosis.Prostate cancer and prostatic diseases · 2021Article
- Residential proximity to pesticide application as a risk factor for childhood central nervous system tumors.Environmental research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
In a population-based case-control study in California's intensely agricultural Central Valley (2005-2006), the authors investigated relations between environmental pesticide/fungicide exposure and prostate cancer. Cases (n = 173) were obtained from a population-based cancer registry, and controls (n = 162) were obtained from Medicare listings and tax assessor mailings. Past ambient exposures to pesticides/fungicides were derived from residential history and independently recorded pesticide and land-use data, using a novel geographic information systems approach. In comparison with unexposed persons, increased risks of prostate cancer were observed among persons exposed to compounds which may have prostate-specific biologic effects (methyl bromide (odds ratio = 1.62, 95% confidence interval: 1.02, 2.59) and a group of organochlorines (odds ratio = 1.64, 95% confidence interval: 1.02, 2.63)) but not among those exposed to other compounds that were included as controls (simazine, maneb, and paraquat dichloride). The authors assessed the possibility of selection bias due to less-than-100% enrollment of eligible cases and controls (a critical methodological concern in studies of this kind) and determined that there was little evidence of bias affecting the estimated effect size. This study provides evidence of an association between prostate cancer and ambient pesticide exposures in and around homes in intensely agricultural areas. The associations appear specific to compounds with a plausible biologic role in prostate carcinogenesis.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.