ArticleGenomics2011
Investigating the genome diversity of B. cereus and evolutionary aspects of B. anthracis emergence.
Article in Genomics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Comprehensive characterization and genome-resolved insights into the probiotic potential of Bacillus sp. KNSH39 isolated from Litopenaeus vannamei intestine.World journal of microbiology & biotechnology · 2026Article
- Comprehensive genomic analysis of a novelMicrobiology spectrum · 2026Article
- The Food Poisoning Toxins ofToxins · 2021Review
- A Unique Isolation of a Lytic Bacteriophage InfectedMicroorganisms · 2020Article
- Molecular and Genomic Characterization of PFAB2: A Non-virulentCurrent genomics · 2019Article
- Adaptive Strategies ofIndian journal of microbiology · 2018Article
- Whole-Genome Characterization of Bacillus cereus Associated with Specific Disease Manifestations.Infection and immunity · 2018Article
- Pan-genome and phylogeny of Bacillus cereus sensu lato.BMC evolutionary biology · 2017Article
- Xenobiotic-metabolizing enzymes in Bacillus anthracis: molecular and functional analysis of a truncated arylamine N-acetyltransferase isozyme.British journal of pharmacology · 2017Article
- Article
- Identification and validation of specific markers of Bacillus anthracis spores by proteomics and genomics approaches.Molecular & cellular proteomics : MCP · 2014Article
- Divergence of protein-coding capacity and regulation in the Bacillus cereus sensu lato group.BMC bioinformatics · 2014Article
- Bacillus "next generation" diagnostics: moving from detection toward subtyping and risk-related strain profiling.Frontiers in microbiology · 2013Article
- Genetic barcodes for improved environmental tracking of an anthrax simulant.Applied and environmental microbiology · 2012Article
- Certhrax toxin, an anthrax-related ADP-ribosyltransferase from Bacillus cereus.The Journal of biological chemistry · 2012Article
- Article
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
Here we report the use of a multi-genome DNA microarray to investigate the genome diversity of Bacillus cereus group members and elucidate the events associated with the emergence of Bacillus anthracis the causative agent of anthrax-a lethal zoonotic disease. We initially performed directed genome sequencing of seven diverse B. cereus strains to identify novel sequences encoded in those genomes. The novel genes identified, combined with those publicly available, allowed the design of a "species" DNA microarray. Comparative genomic hybridization analyses of 41 strains indicate that substantial heterogeneity exists with respect to the genes comprising functional role categories. While the acquisition of the plasmid-encoded pathogenicity island (pXO1) and capsule genes (pXO2) represents a crucial landmark dictating the emergence of B. anthracis, the evolution of this species and its close relatives was associated with an overall shift in the fraction of genes devoted to energy metabolism, cellular processes, transport, as well as virulence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.