GuidelineEuropean child & adolescent psychiatry2011
European clinical guidelines for Tourette syndrome and other tic disorders. Part II: pharmacological treatment.
Guideline in European child & adolescent psychiatry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 4 registered trials, which are not on this map. Cited by 149 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Behavioral Therapy for Children and Adolescents With Tourette Syndrome: A Randomized Controlled Trial in Taiwan
Efficacy and Safety of Washed Microbiota Transplantation for Tourette's Syndrome
A Randomised, Double-blind, Placebo-controlled, Trial of Rhythmic 10Hz Median Nerve Stimulation for the Suppression of the Urge-to-tic and Reduction of Tics in Individuals With Tourette Syndrome and Chronic Tic Disorder
Finalizing and Testing an Online Therapist Training and Assistance Program to Facilitate Implementation of Comprehensive Behavioral Intervention for Tic Disorders
Who cites it
149 citing papers in PubMed, 11 syntheses or guidelines pooled it, 466 citations in OpenAlex.
- Digitally enabled therapy for chronic tic disorders and Tourette Syndrome: a systematic review and economic evaluation.Health technology assessment (Winchester, England) · 2026Pooled it
- European clinical guidelines for Tourette syndrome and other tic disorders-version 2.0. Part II: psychological interventions.European child & adolescent psychiatry · 2022Guideline
- Investigating Acupoint Selection and Combinations of Acupuncture for Tic Disorders: An Association Rule Mining and Network Analysis Study.Frontiers in neurology · 2022Pooled it
- The Efficacy of Cognitive Behavioral Therapy for Tic Disorder: A Meta-Analysis and a Literature Review.Frontiers in psychology · 2022Pooled it
- Traditional Chinese Medicine Strategy for Patients with Tourette Syndrome Based on Clinical Efficacy and Safety: A Meta-Analysis of 47 Randomized Controlled Trials.BioMed research international · 2021Pooled it
- Relaxation therapy as a treatment for tics in patients with Tourette syndrome: a systematic literature review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020Pooled it
- Striatal dopaminergic alterations in Tourette's syndrome: a meta-analysis based on 16 PET and SPECT neuroimaging studies.Translational psychiatry · 2018Pooled it
- The prevalence of tic disorders for children in China: A systematic review and meta-analysis.Medicine · 2016Pooled it
- Systematic review: pharmacological treatment of tic disorders--efficacy of antipsychotic and alpha-2 adrenergic agonist agents.Neuroscience and biobehavioral reviews · 2013Pooled it
- European clinical guidelines for Tourette syndrome and other tic disorders. Part IV: deep brain stimulation.European child & adolescent psychiatry · 2011Guideline
- The effectiveness of habit reversal therapy in the treatment of Tourette syndrome and other chronic tic disorders: a systematic review.Functional neurologyPooled it
- Online remote behavioural intervention for tics in 9- to 17-year-olds: the ORBIT RCT with embedded process and economic evaluation.Health technology assessment (Winchester, England) · 2023Trial
- Efficacy and Safety of Fixed-Dose Deutetrabenazine in Children and Adolescents for Tics Associated With Tourette Syndrome: A Randomized Clinical Trial.JAMA network open · 2021Trial
- Combined habit reversal training and exposure response prevention in a group setting compared to individual training: a randomized controlled clinical trial.European child & adolescent psychiatry · 2019Trial
- Randomized, Double-Blind, Placebo-Controlled Trial Demonstrates the Efficacy and Safety of Oral Aripiprazole for the Treatment of Tourette's Disorder in Children and Adolescents.Journal of child and adolescent psychopharmacology · 2017Trial
- [Efficacy of clonidine transdermal patch in treatment of moderate to severe tic disorders in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Trial
- Trial
- Medication use and treatment patterns in children and adolescents with chronic tic disorders: an EMTICS study.European child & adolescent psychiatry · 2026Article
- Development of a tic service model for children and young people in England: a Delphi study.BMJ open · 2026Article
- Digital-Supported Delivery of Behavioural Therapy for Patients with Tic Disorders: A Narrative Review.Brain sciences · 2026Review
89 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
11 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To develop a European guideline on pharmacologic treatment of Tourette syndrome (TS) the available literature was thoroughly screened and extensively discussed by a working group of the European Society for the Study of Tourette syndrome (ESSTS). Although there are many more studies on pharmacotherapy of TS than on behavioral treatment options, only a limited number of studies meets rigorous quality criteria. Therefore, we have devised a two-stage approach. First, we present the highest level of evidence by reporting the findings of existing Cochrane reviews in this field. Subsequently, we provide the first comprehensive overview of all reports on pharmacological treatment options for TS through a MEDLINE, PubMed, and EMBASE search for all studies that document the effect of pharmacological treatment of TS and other tic disorders between 1970 and November 2010. We present a summary of the current consensus on pharmacological treatment options for TS in Europe to guide the clinician in daily practice. This summary is, however, rather a status quo of a clinically helpful but merely low evidence guideline, mainly driven by expert experience and opinion, since rigorous experimental studies are scarce.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.