ArticleMolecular and cellular biochemistry2011
Molecular cloning, expression, and regulation of goose leptin receptor gene in adipocytes.
Article in Molecular and cellular biochemistry, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 23 citations in OpenAlex.
- The DuckAnimals : an open access journal from MDPI · 2023Article
- The differentiation of preadipocytes and gene expression related to adipogenesis in ducks (Anas platyrhynchos).PloS one · 2018Article
- Leptin Elicits LTCFrontiers in immunology · 2018Article
- Isolation, culture and differentiation of duck (Anas platyrhynchos) preadipocytes.Cytotechnology · 2015Article
- Expression pattern of L-FABP gene in different tissues and its regulation of fat metabolism-related genes in duck.Molecular biology reports · 2013Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
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Abstract
A full-length cDNA encoding the goose (Anser anser) leptin receptor (LEPR) was cloned and sequenced. The goose LEPR gene encodes a 1,156-amino acid protein containing a signal peptide, a single transmembrane domain and specific motifs involving putative leptin-binding and signal transduction. The deduced goose LEPR protein shows more than 90% identity to duck and 75% identity to chicken and turkey. Quantitative real-time analysis reveals that the goose LEPR is predominantly expressed in brain. The expression of LEPR in goose adipocytes can be up-regulated by oleic acid in vitro. Moreover, the expression levels of genes, which have been demonstrated to be related to adipocyte differentiation, are down-regulated in LEPR-knockdown adipocytes, indicating LEPR's potential role in adipocyte differentiation in goose.
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Registered trials
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