Trial reportEuropean journal of applied physiology2011
Cold application for neuromuscular recovery following intense lower-body exercise.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02506283 (The Effect of Cryotherapy on Recovery and Performance), which is not on this map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Cryotherapy on Recovery and Performance: A Randomized Controlled Double Blind Trial
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Effects of Various Physical Interventions on Reducing Neuromuscular Fatigue Assessed by Electromyography: A Systematic Review and Meta-Analysis.Frontiers in bioengineering and biotechnology · 2021Pooled it
- Can Water Temperature and Immersion Time Influence the Effect of Cold Water Immersion on Muscle Soreness? A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- The Effect of Post-Exercise Cryotherapy on Recovery Characteristics: A Systematic Review and Meta-Analysis.PloS one · 2015Pooled it
- Isolated and Combined Effects of Cold, Heat and Hypoxia Therapies on Muscle Recovery Following Exercise-Induced Muscle Damage.Sports medicine (Auckland, N.Z.) · 2025Review
- Cryocompression Therapy for Recovery from Eccentric Exercise-Induced Muscle Damage in Healthy Young Men.Sports (Basel, Switzerland) · 2025Article
- Effects of thermal interventions on skeletal muscle adaptations and regeneration: perspectives on epigenetics: a narrative review.European journal of applied physiology · 2025Review
- Direct Effect of Local Cryotherapy on Muscle Stimulation, Pain and Strength in Male Office Workers with Lateral Epicondylitis, Non-Randomized Clinical Trial Study.Healthcare (Basel, Switzerland) · 2022Article
- Functional Impact of Post-exercise Cooling and Heating on Recovery and Training Adaptations: Application to Resistance, Endurance, and Sprint Exercise.Sports medicine - open · 2022Review
- Effect of cold and heat therapies on pain relief in patients with delayed onset muscle soreness: A network meta-analysis.Journal of rehabilitation medicine · 2022Article
- Thermal Infrared Imaging Can Differentiate Skin Temperature Changes Associated With Intense Single Leg Exercise, But Not With Delayed Onset of Muscle Soreness.Journal of sports science & medicine · 2020Article
- Non-invasive Assessments of Subjective and Objective Recovery Characteristics Following an Exhaustive Jump Protocol.Journal of visualized experiments : JoVE · 2017Article
- Cooling interventions for athletes: An overview of effectiveness, physiological mechanisms, and practical considerations.Temperature (Austin, Tex.) · 2017Review
- What are the Physiological Mechanisms for Post-Exercise Cold Water Immersion in the Recovery from Prolonged Endurance and Intermittent Exercise?Sports medicine (Auckland, N.Z.) · 2016Review
- The effect of local cryotherapy on subjective and objective recovery characteristics following an exhaustive jump protocol.Open access journal of sports medicine · 2016Article
- Stretching versus transitory icing: which is the more effective treatment for attenuating muscle fatigue after repeated manual labor?European journal of applied physiology · 2014Article
- Pain during and within hours after exercise in healthy adults.Sports medicine (Auckland, N.Z.) · 2014Review
- Effects of lymphatic drainage and local cryo exposition regeneration after high-intensive exercises.Muscles, ligaments and tendons journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study examined the effects of cold therapy (COLD) on recovery of voluntary and evoked contractile properties following high-intensity, muscle-damaging and fatiguing exercise. Ten resistance-trained males performed 6 × 25 maximal concentric/eccentric muscle contractions of the dominant knee extensors (KE) followed by a 20-min recovery (COLD v control) in a randomized cross-over design. Voluntary and evoked neuromuscular properties of the right KE, ratings of perceived muscle soreness (MS) and pain, and blood markers for muscle damage were measured pre- and post-exercise, and immediately post-recovery, 2, 24 and 48-h post-recovery. Exercise resulted in decrements in voluntary and evoked torque, increased MS and elevated muscle damage markers (p < 0.05). Measures of maximal voluntary contraction (MVC) or voluntary activation (VA) were not significantly enhanced by COLD (p > 0.05). Activation of right KE decreased post-exercise with increased activation of biceps femoris (BF) (p < 0.05). However, no significant differences were evident between conditions of activation of KE and hamstrings at any time point (p > 0.05). No significant differences were observed between conditions for creatine kinase or asparate aminotransferase (p > 0.05). However, perceptual ratings of pain were significantly (p < 0.05) lower following COLD compared to control. In conclusion, following damage to the contractile apparatus, COLD did not significantly hasten the recovery of peripheral contractile trauma. Despite no beneficial effect of COLD on recovery of MVC, perceptions of pain were reduced following COLD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.