Evidence map›Paper›PMID 21445552›Full record

ReviewNeuropsychology review2011

Magnetic resonance-based imaging in animal models of fetal alcohol spectrum disorder.

Shonagh K O'Leary-Moore, Scott E Parnell, Robert J Lipinski, Kathleen K Sulik

Abstract readReview
In one paragraph

Review in Neuropsychology review, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. The Role of the Hedgehog Pathway in Alcohol-Induced Birth Defects.Advances in experimental medicine and biology · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Gene-alcohol interactions in birth defects.Current topics in developmental biology · 2023
    Article
  13. Alcohol and the Brain.Nutrients · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shonagh K O'Leary-MooreBowles Center for Alcohol Studies, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. somoore@med.unc.edu
Scott E Parnell
Robert J Lipinski
Kathleen K Sulik

Funding

UNC ARC Information/Dissemination CoreP60AA011605 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Thomas L. Kash · 2003 to 2026
$46.3M
UNC MRDD Research CenterP30HD003110 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PIVEN, JOSEPH · 1985 to 2012
$28.7M
X-RAY RESEARCH AND DEVELOPMENT WITH/WITHOUT LIVE ANIMALSP41RR005959 · NCRR · DUKE UNIVERSITY · PI MCCONNELL, GEORGE C · 1990 to 2011
$16.0M
Supplement to Molecular and Cellular Studies on Alcohol's ActionsT32AA007573 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FULTON T CREWS, Thomas L. Kash · 1997 to 2026
$9.3M
Duke University Molecular Imaging CenterR24CA092656 · NCI · DUKE UNIVERSITY · PI JOHNSON, GEORGE ALLAN · 2001 to 2006
$3.7M
MAGNETIC RESONANCE AND DIFFUSION TENSOR IMAGING OF A MOUSE FASD MODEL U01U01AA017124 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SULIK, KATHLEEN K · 2007 to 2011
$1.2M
NCI NIH HHS R24 CA092656NCI NIH HHS U24 CA0292656NCRR NIH HHS P41 RR005959NIAAA NIH HHS AA007573NIAAA NIH HHS P60 AA011605NIAAA NIH HHS T32 AA007573NIAAA NIH HHS U01 AA017124NICHD NIH HHS P30 HD003110PHS HHS NICDH 03110PHS HHS P41 05959
6 · The paper itself

Abstract

Magnetic resonance imaging (MRI) techniques, such as magnetic resonance microscopy (MRM), diffusion tensor imaging (DTI), and magnetic resonance spectroscopy (MRS), have recently been applied to the study of both normal and abnormal structure and neurochemistry in small animals. Herein, findings from studies in which these methods have been used for the examination of animal models of Fetal Alcohol Spectrum Disorder (FASD) are discussed. Emphasis is placed on results of imaging studies in fetal and postnatal mice that have highlighted the developmental stage dependency of prenatal ethanol exposure-induced CNS defects. Consideration is also given to the promise of methodological advances to allow in vivo studies of aberrant brain and behavior relationships in model animals and to the translational nature of this work.

Indexed as

BrainDisease Models, AnimalAnimalsBrain MappingDevelopmental DisabilitiesDiagnostic ImagingEthanolFacial AsymmetryFemaleFetal Alcohol Spectrum DisordersImaging, Three-DimensionalMaleMicePregnancyPrenatal Exposure Delayed EffectsEthanol

Identifiers

PMID21445552
PMCPMC3445286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.