ArticleTherapeutics and clinical risk management2011
A causative link between periodontal disease and glomerulonephritis: a preliminary study.
Article in Therapeutics and clinical risk management, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- The relationship between periodontitis and proteinuria in chronic kidney disease: A review.Medicina oral, patologia oral y cirugia bucal · 2025Review
- Association between gingival bleeding and hematuria as biomarkers of periodontitis and renal disease: a review.Odontology · 2024Review
- Cross-sectional characterization of renal function in cats with caudal stomatitis.Journal of feline medicine and surgery · 2023Article
- Proteinuria in Apparently Healthy Elderly Dogs: Persistency and Comparison Between Free Catch and Cystocentesis Urine.Journal of veterinary internal medicine · 2017Article
- Urinary enzymatic markers (N-acetyl-beta-D-glucosaminidase) in assessing the tubulointerstitial compartment in chronic glomerulonephritis related to odontogenic foci.Wiener klinische Wochenschrift · 2016Article
- Global scientific vision with local vigilance: renal transplantation in developing countries.Nephro-urology monthly · 2015Review
- Erysipelas-associated glomerulonephritis; a diagnostic puzzle.Journal of nephropharmacology · 2014Article
- Correlation between periodontitis and chronic kidney disease in Korean adults.Kidney research and clinical practice · 2013Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriodontal disease has been associated with a number of systemic diseases. A high prevalence of periodontitis among individuals with chronic kidney diseases and end-stage renal disease has been reported. However, no association between periodontal diseases and glomerulonephritis has previously been investigated.
objectiveThe aim of this study was to assess the severity and possible role of periodontitis in a group of patients with unknown primary glomerulonephritis.
methodsTen patients with unknown primary glomerulonephritis, and who had a renal biopsy with stable renal function and serum creatinine <1.6 mg/dL, were recruited. Severity of the periodontal disease was clinically measured with plaque index (PI), gingival index (GI), and periodontal pocket depth (PD). The subjects received appropriate dental treatments where indicated. The patients were also put on angiotensin-converting enzyme inhibitor or angiotensin receptor blockers for controlling blood pressure and proteinuria. Six months following appropriate periodontal treatment, renal function, degree of proteinuria, and level of C-reactive protein (CRP) were measured in each individual.
resultsThe median age of the patients was 30 (15.8) years. The median urine protein excretion was lower following the periodontal therapy (P=008). Prior to the dental and/or periodontal therapies, the median PI, PD, and GI were 57.5%, 4.3, and 1.1, respectively. The majority of the patients had advanced periodontal disease. In four patients, +2/+3 CRP turned negative after periodontal treatment.
conclusionsThe present study revealed that a causative link might exist between periodontal disease and glomerulonephritis.
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