ArticleNature genetics2011
Next-generation association studies for complex traits.
Article in Nature genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of genome-wide association studies identifies common variants in CTNNA2 associated with excitement-seeking.Translational psychiatry · 2011Pooled it
- How local reference panels improve imputation in French populations.Scientific reports · 2024Article
- Article
- Sequencing and imputation in GWAS: Cost-effective strategies to increase power and genomic coverage across diverse populations.Genetic epidemiology · 2020Article
- Article
- Do we need diagnostic strategies enhanced with genetic information for ischemic heart disease?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- A study of Kibbutzim in Israel reveals risk factors for cardiometabolic traits and subtle population structure.European journal of human genetics : EJHG · 2018Article
- Article
- A combined reference panel from the 1000 Genomes and UK10K projects improved rare variant imputation in European and Chinese samples.Scientific reports · 2016Article
- EM Adaptive LASSO-A Multilocus Modeling Strategy for Detecting SNPs Associated with Zero-inflated Count Phenotypes.Frontiers in genetics · 2016Article
- Suppression Subtractive Hybridization Versus Next-Generation Sequencing in Plant Genetic Engineering: Challenges and Perspectives.Molecular biotechnology · 2015Review
- Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants.Nature communications · 2014Article
- Calcium intake and ion transporter genetic polymorphisms interact in human colorectal neoplasia risk in a 2-phase study.The Journal of nutrition · 2014Article
- Using population isolates in genetic association studies.Briefings in functional genomics · 2014Review
- Analysis of coding variants identified from exome sequencing resources for association with diabetic and non-diabetic nephropathy in African Americans.Human genetics · 2014Article
- Genomic view of bipolar disorder revealed by whole genome sequencing in a genetic isolate.PLoS genetics · 2014Article
- A large-scale screen for coding variants predisposing to psoriasis.Nature genetics · 2014Article
- Using genetically isolated populations to understand the genomic basis of disease.Genome medicine · 2014Article
- In search of low-frequency and rare variants affecting complex traits.Human molecular genetics · 2013Review
- Inference of identity by descent in population isolates and optimal sequencing studies.European journal of human genetics : EJHG · 2013Article
Corrections and comments
- Comment on
Authors and funding
1 author.
Funding
Abstract
A new study successfully applies complementary whole-genome sequencing and imputation approaches to establish robust disease associations in an isolated population. This strategy is poised to help elucidate the role of variants at the low end of the allele frequency spectrum in the genetic architecture of complex traits.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.