Evidence map›Paper›PMID 21444708›Full record

ArticleAntimicrobial agents and chemotherapy2011

Gentian violet exhibits activity against biofilms formed by oral Candida isolates obtained from HIV-infected patients.

Rana S Traboulsi, Pranab K Mukherjee, Jyotsna Chandra, Robert A Salata, Richard Jurevic, Mahmoud A Ghannoum

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rana S TraboulsiCenter for Medical Mycology, Department of Dermatology, Division of Infectious Diseases and HIV Medicine, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Pranab K Mukherjee
Jyotsna Chandra
Robert A Salata
Richard Jurevic
Mahmoud A Ghannoum
Case Western Reserve University · USUniversity Hospitals Case Medical Center · US

Funding

Low-Dose High-Resolution Dental RadiographyR44DE017846 · NIDCR · DXRAY, INC. · PI HARTSOUGH, NEAL EUGENE · 2010 to 2011
$1.1M
Role of extracellular matrix proteins in Candida biofilm formationR21AI074077 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI MUKHERJEE, PRANAB KUMAR · 2009 to 2010
$432k
Low-Dose High-Resolution Dental RadiographyR43DE017846 · NIDCR · DXRAY, INC. · PI HARTSOUGH, NEAL EUGENE · 2007 to 2007
$198k
NIAID NIH HHS 1R21AI074077-01A2NIAID NIH HHS R21 AI074077NIDCR NIH HHS R01-DE017846NIDCR NIH HHS R43 DE017846NIDCR NIH HHS R44 DE017846
6 · The paper itself

Abstract

The effect of gentian violet against Candida albicans and non-Candida albicans biofilms formed on polymethylmethacrylate strips was evaluated using a dry weight assay and confocal laser scanning microscopy. The ability of gentian violet to inhibit Candida albicans germination was also assessed. Gentian violet activity against Candida biofilms was demonstrated by a reduction in dry weight, disruption of biofilm architecture, and reduced biofilm thickness. Additionally, gentian violet inhibited Candida germination in a concentration-dependent manner.

Indexed as

Anti-Infective Agents, LocalBiofilmsCandida albicansCandidiasis, OralDose-Response Relationship, DrugGentian VioletHIV InfectionsHumansMicroscopy, ConfocalAnti-Infective Agents, LocalGentian Violet

Identifiers

PMID21444708
PMCPMC3101405
OpenAlexW2126177739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.